| 年龄相关性黄斑变性发病危险因素研究进展 |
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| 引用本文： | 杨桢,杨小丽. 年龄相关性黄斑变性发病危险因素研究进展[J]. 国际眼科杂志, 2014, 14(6): 1054-1057 |
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| 作者姓名： | 杨桢 杨小丽 |
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| 作者单位： | 中国四川省南充市,川北医学院附属医院眼科;中国四川省南充市,川北医学院附属医院眼科 |
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| 摘 要： | 年龄相关性黄斑变性（age-related macular degeneration，AMD）是一种主要的全球性致盲眼病之一。AMD是一种多因素的疾病，主要的危险因素包括年龄，吸烟，白内障手术史，环境因素，营养因素，遗传标志，包括基因调节补体，脂质，血管生成和细胞外基质的途径。除了治疗外，AMD的流行病学，危险因素和遗传学研究已有重大进展。本文将AMD发病的危险因素作简要综述。
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| 关 键 词： | 年龄相关性黄斑变性 危险因素 流行病学 |
| 收稿时间： | 2014-03-19 |
| 修稿时间： | 2014-05-14 |
Progress in the study of risk factors of age-related macular degeneration |
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| Zhen Yang and Xiao-Li Yang. Progress in the study of risk factors of age-related macular degeneration[J]. International Eye Science, 2014, 14(6): 1054-1057 |
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| Authors: | Zhen Yang and Xiao-Li Yang |
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| Affiliation: | Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan Province, China;Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan Province, China |
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| Abstract: | Age-related macular degeneration(AMD)is one of a leading worldwide cause of blindness. AMD is a multifactorial disease, and major risk factors include increasing age, current smoking, previous cataract surgery, environmental factors, nutritional factors, genetic markers through genetic regulate complement, lipid, angiogenesis and extracellular matrix. In addition to treatment, epidemiology, risk factors and genetics research of AMD have been significantly progressed. This article will review risk factors of AMD. |
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| Keywords: | age-related macular degeneration risk factors epidemiology |
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