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Nodular lichen myxoedematous: a new adverse event associated with ustekinumab
Authors:Trinidad Montero-Vilchez  Antonio Martinez-Lopez  Carlos Cuenca-Barrales  Aurelio Martin-Castro  Alejandro Molina-Leyva  Salvador Arias-Santiago
Institution:1. Department of Dermatology at Hospital, Universitario Virgen de las Nieves, Granada, Spain;2. Department of Dermatology at Hospital, Universitario San Cecilio, Granada, Spain;3. Department of Pathology at Hospital, Universitario Virgen de las Nieves, Granada, Spain
Abstract:Nodular lichen myxoedematosus is a localised form of lichen myxoedematosus, a chronic idiopathic cutaneous mucinosis of known aetiology. Ustekinumab is a human interleukin-12/23 monoclonal antibody that could directly or indirectly increase mucin production. Herein, we report for the first time a case of nodular lichen myxoedematosus associated with ustekinumab.
Keywords:biological therapy  drug toxicity  interleukin-23  mucins  scleromyxoedema  toxicity  ustekinumab
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