Late-onset interstitial nephritis in a patient with drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms |
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| Authors: | Yuko Higashi Naoko Baba Haruhito Yoshimine Ikuyo Sakaguchi Takuro Kanekura |
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| Affiliation: | 1. Department of, Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan;2. Department of, Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan;3. Department of Dermatology, Saiseikai Sendai Hospital, Satsumasendai, Japan |
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| Abstract: | Drug-induced hypersensitivity syndrome (DIHS), also referred to as drug reaction with eosinophilia and systemic symptoms (DRESS), is a severe hypersensitivity drug reaction affecting the skin and multiple internal organ systems. We report a 47-year-old man with DIHS/DRESS and comorbidities (fulminant type 1 diabetes mellitus, valsartan-induced photosensitivity, vitiligo and acute interstitial nephritis). Although acute interstitial nephritis usually appears in the early phase, his is a rare case of acute interstitial nephritis more than 2 years after the onset of DIHS/DRESS. |
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| Keywords: | drug reaction with eosinophilia and systemic symptoms drug-induced hypersensitivity syndrome interstitial nephritis photosensitivity vitiligo |
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