重金属中毒与儿童肾损伤

随着经济发展相伴随的环境污染全球化，儿童重金属中毒日益成为全球性健康问题。重金属中毒可致肾损伤，由于儿童早期临床表现不明显或缺乏特异性改变，易误诊和漏诊。早预防、早发现、早干预中毒性肾损伤有利于儿童健康成长及肾脏功能的恢复。该文综述了重金属中毒性肾损伤的机制及儿童常见的铅、汞、镉、铬4种重金属中毒致肾损伤的临床表现、诊断与防治。

Heavy metal poisoning and renal injury in children

Along with global environmental pollution resulting from economic development, heavy metal poisoning in children has become an increasingly serious health problem in the world. It can lead to renal injury, which tends to be misdiagnosed due to the lack of obvious or specific early clinical manifestations in children. Early prevention, diagnosis and intervention are valuable for the recovery of renal function and children''s good health and growth. This paper reviews the mechanism of renal injury caused by heavy metal poisoning in children, as well as the clinical manifestations, diagnosis, and prevention and treatment of renal injury caused by lead, mercury, cadmium, and chromium.