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“瘀”、“毒”从化——心脑血管血栓性疾病病因病机
引用本文:史大卓,徐浩,殷惠军,张京春,陈可冀.“瘀”、“毒”从化——心脑血管血栓性疾病病因病机[J].中西医结合学报,2008,6(11):1105-1108.
作者姓名:史大卓  徐浩  殷惠军  张京春  陈可冀
作者单位:1. 中国中医科学院西苑医院心血管中心,北京,100091
2. 中日友好医院全国中西医结合心血管病中心,北京,100029
基金项目:国家重点基础研究发展计划(973计划)
摘    要:心脑血管血栓性疾病发病过程中的血小板活化、黏附、聚集和血栓形成,传统中医药学多将其病因病机归于"血脉瘀阻"的范畴;但组织坏死、过氧化应激损伤、炎症反应等病理改变,远非单一"血瘀"病因所能概括。根据传统中医"毒"邪病因的认识,心脑血管血栓性疾病发病当存在"毒"邪致病或"瘀"、"毒"从化互结致病的病因病机。注重"瘀"、"毒"病因在心脑血管血栓性疾病发病过程中的相互兼夹、相互从化,探索中医治法方药,对丰富心脑血管血栓性疾病的中医病因学,提高临床疗效,具有重要意义。

关 键 词:心血管疾病  血栓形成  血瘀

Combination and transformation of toxin and blood stasis in etiopathogenesis of thrombotic cerebrocardiovascular diseases
Da-zhuo SHI,Hao XU,Hui-jun YIN,Jing-chun ZHANG,Ke-ji CHEN.Combination and transformation of toxin and blood stasis in etiopathogenesis of thrombotic cerebrocardiovascular diseases[J].Journal of Chinese Integrative Medicine,2008,6(11):1105-1108.
Authors:Da-zhuo SHI  Hao XU  Hui-jun YIN  Jing-chun ZHANG  Ke-ji CHEN
Institution:Da-zhuo SHI1,Hao XU2,Hui-jun YIN1,Jing-chun ZHANG1,Ke-ji CHEN1 1.Cardiovascular Center,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China2.National Integrated Center of Cardiovascular Disease,China-Japan Friendship Hospital,Beijing 100029,China
Abstract:According to the basic theory of traditional Chinese medicine(TCM),the pathogenetic factors such as platelet activation,adhesion,congregation and thrombosis fall into the category of blood stasis,while the pathological changes such as tissue necrosis,oxidative stress injury and inflammation,etc,are far beyond the etiological category of blood stasis.The toxin or the combination and transformation of toxin and blood stasis of TCM are involved in the pathogenesis of thrombotic cerebrocardiovascualr diseases.I...
Keywords:cardiovascular diseases  thrombosis  blood stasis  
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