| 庆大霉素毒性作用对肝肾的影响及其保护的形态学研究 |
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| 引用本文： | 黄巨恩,徐志文,陈纡,梁祖鼎. 庆大霉素毒性作用对肝肾的影响及其保护的形态学研究[J]. 解剖科学进展, 2000, 6(3): 260-263 |
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| 作者姓名： | 黄巨恩 徐志文 陈纡 梁祖鼎 |
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| 作者单位： | 1. 广西医科大学组胚教研室,南宁,530021
2. 第一附属医院耳鼻咽喉科 |
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| 摘 要： | 通过肌注庆大霉素使豚鼠出现毒性损害 ,同时以碱性成纤维细胞生长因子作为拮抗剂 ,观察庆大霉素毒性作用对肝肾的形态学影响及其碱性成纤维细胞生长因子的保护作用。结果表明 :碱性成纤维细胞生长因子对庆大霉素肾毒性有一定的保护作用
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| 关 键 词： | 庆大霉素 肾毒性 碱性成纤维细胞生长因子 对抗作用 豚鼠 |
Morphological Studies of Toxitic Effects of Gentamicin to Livers and Kidneys and its Protective Function |
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| Huang Juen,Xu Zhiwen,Chen Yu. Morphological Studies of Toxitic Effects of Gentamicin to Livers and Kidneys and its Protective Function[J]. Progress of Anatomical Sciences, 2000, 6(3): 260-263 |
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| Authors: | Huang Juen Xu Zhiwen Chen Yu |
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| Affiliation: | Huang Juen,Xu Zhiwen,Chen Yu;(Department of Histology and Embrology, Guangxi Medcial University, Nanning 530021) |
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| Abstract: | By injecting gentamicin into guinea pig muscularly, toxitic damages were caused. On the same time, basic Fibroblast Growth Factor (bFGF) were used as antagonist agents. Morphological influences of toxitic effects gentamicin to livers and kidneys and protective effects of bFGF were observed. The results showed that bFGF had antagonistic effects to nephrotoxity caused by Gentamicin to a certain degree. |
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| Keywords: | gentamicin nephrotoxity bFGF antagonistic effects guinea pig |
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