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四川彝族的起源初探--来自人类白细胞抗原-B基因的线索
引用本文:许铭炎,陈耿臻,李军,陈子平,傅玉才.四川彝族的起源初探--来自人类白细胞抗原-B基因的线索[J].汕头大学医学院学报,2005,18(4):234-237.
作者姓名:许铭炎  陈耿臻  李军  陈子平  傅玉才
作者单位:1. 汕头大学医学院病原生物学教研室
2. 汕头大学医学院第一附属医院普外科,广东,汕头,515041
3. 诏安县医院,福建,诏安,363500
摘    要:目的:根据人类白细胞抗原(HLA)-B基因频率,探讨四川彝族的民族起源。方法:收集四川彝族群体的HLA-B基因频率和已报道国内其他主要民族人群的札A-B基因数据,运用唧口对HLA-B数据进行聚类分析。主成分分析由SPSS11.0完成。结果:从聚类树型结构图可知。我国主要民族明显分为南北两大群,四川彝族虽处于北方人群一组。但在遗传距离上介于南北方人群之间。主成分分析发现。彝族处于汉藏语系群体之中。与藏族群体关系最近。结论:从HLA-B基因的角度分析。四川彝族的HLA-B遗传特征表现为源于北方,与藏族关系密切。

关 键 词:四川彝族  人类白细胞抗原-B  基因频率  聚类分析  主成分分析
文章编号:1007-4716(2005)04-0234-04
收稿时间:2005-10-18
修稿时间:2005年10月18

The Origin of Sichuan Yi Ethnic Group Inferred by Human Leukocyte Antigen-B Gene Study
XU Ming-yan,CHEN Geng-zhen,LI Jun,CHEN Zi-ping,FU Yu-cai.The Origin of Sichuan Yi Ethnic Group Inferred by Human Leukocyte Antigen-B Gene Study[J].Journal of Shantou University Medical College,2005,18(4):234-237.
Authors:XU Ming-yan  CHEN Geng-zhen  LI Jun  CHEN Zi-ping  FU Yu-cai
Abstract:Objective: To study the origin of Sichuan Yi ethnic group according to human leukocyte antigen(HLA)-B gene frequency.Methods: HLA-B gene frequencies of Yi ethnic group and other related Chinese ethnic groups were col-lected.Cluster analysis and principle component analysis were performed by PHYLIP software and SPSS11.0 respective-ly.Results: From the phylogenetic tree formed by cluster analysis,mainly Chinese ethnic groups could be divided into Southern and Northern population.Although Sichuan Yi ethnic group was clustered with the Northern population,the ge-netic distance was between Southern and Northern population.By principle component analysis,Yi ethnic group showed close to Tibetan in the Han-Tibet speaking population.Conclusion: From the clue of HLA-B gene,Yi ethnic group shows the genetic characteristic of Northern Chinese and has a close relationship with Tibetan.
Keywords:Sichuan Yi ethnic group  human leukocyte antigen-B  gene frequency  cluster analysis  principle component analysis
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