Incidental prostatic carcinoma: Morphometry correlated with histological grade |
| |
| Authors: | Ryuichi Yatani Taizo Shiraishi Kaneyoshi Akazaki Takuji Hayashi Lance K. Heilbrun Grant N. Stemmermann |
| |
| Affiliation: | (1) Department of Pathology, Mie University School of Medicine, 2-174 Edobashi, 514 Tsu, Mie-ken, Japan;(2) Aichi Cancer Center Research Institute, 81-1159 Kanokoden, Tashiro-cho, Chigusa, 464 Nagoya, Aichi, Japan;(3) Laboratory Department, Kuakini Medical Center, 347 N. Kuakini Street, 96817 Honolulu, HI, USA;(4) Japan-Hawaii Cancer Study, 347 N. Kuakini Street, 96817 Honolulu, HI, USA |
| |
| Abstract: | Summary The histological grades of prostatic carcinoma, as defined by Gleason, were correlated with three methods of morphometry in 254 step-sectioned prostates obtained at autopsy. The variables studied were 1) the number of tumours in each prostate; 2) bilaterality and 3) tumour volume. Each characteristic yielded a statistically significant correlation with histological grade. The strongest correlations were obtained using tumour volume. These autopsy studied help to explain the inconsistent results obtained from morphometric analyses of surgical material, and lend support to the Gleason system as a means of predicting tumour behavior.Supported in part by research contracts PH 64-10, NCI-72-3213, N01-CP-53521; Grant R01-CA-33644; and the Grant-in-Aid for Cancer Research (33) from the Ministry of Health and Welfare |
| |
| Keywords: | Incidental prostatic carcinoma Morphometry Histological grading |
| 本文献已被 SpringerLink 等数据库收录！ |
|
