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羟基喜树碱肝动脉化疗栓塞治疗原发性肝癌108例临床分析
引用本文:杨如武,许怀利,王全利,牛惠敏,韩国宏. 羟基喜树碱肝动脉化疗栓塞治疗原发性肝癌108例临床分析[J]. 现代医用影像学, 2008, 17(5): 277-279
作者姓名:杨如武  许怀利  王全利  牛惠敏  韩国宏
作者单位:1. 西电集团医院MR室&消化内科,西安,710077
2. 西安交大医学院卫生统计教研室
3. 咸阳215医院介入治疗中心
4. 第四军医大学西京医院介入治疗中心
摘    要:目的:观察羟基喜树碱(HCPT)为主治疗原发性中晚期肝癌(HCC)的疗效和毒副作用。材料与方法:采用HCPT联合5-Fu、丝裂霉素、阿霉素或顺铂与碘化油混合后治疗中期HCC54例(治疗组),并与不含HCPT方案的TACE组成对照组54例进行对照研究。结果:治疗组患者临床症状缓解,有效率为72.8%,毒副反应发生率低,平均生存率为7.8个月。对照组有效率为51.5%,平均生存率为5.4个月。结论:采用HCPT联合5-Fu、丝裂霉素、阿霉素或顺铂与碘化油混合后介入治疗中晚期HCC,有可能延长患者的生存期,提高生存质量,此方法值得进一步研究。

关 键 词:肝肿瘤/中西医结合疗法  介入栓塞治疗  羟基喜树碱

Observation of Curative Effects of HCPT in Patients with Advanced Hepatic Carcinoma
Yang Ruwu Wang Quanli Niu Huimin Han Guohong. Observation of Curative Effects of HCPT in Patients with Advanced Hepatic Carcinoma[J]. Modern Medical Imagelogy, 2008, 17(5): 277-279
Authors:Yang Ruwu Wang Quanli Niu Huimin Han Guohong
Affiliation:Yang Ruwu~1 Wang Quanli~2 Niu Huimin~3 Han Guohong~4 Department of MR,Xi'an Electro-Group Hospital,710077
Abstract:Purpose:To observe the efficacy and toxicity of combination chemotherapy mainly with hydroxycamptotheciin(HCPT)in the treatment of advanced hepatic carcinom.Materials and Methods:54 cases of advanced hepatic carcinoma were treated with hydroxycamp- totheciin combined with 5-fluorouracil,mitomycin,adriamycin or cisplatin mixed with iodized oil,another 54 cases were set as control groug which was treated with combination without hydroxycamptothecin.Results:In treatment gronp,the clinical symptom remission rat...
Keywords:Liver neoplam/integrated traditional chinese and western therapy  Interventional embolization treatment  Hydroaxycamptotheciine  
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