| 奥曲肽和垂体后叶素治疗食管静脉破裂出血 |
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| 引用本文： | 施文娟,张顺财. 奥曲肽和垂体后叶素治疗食管静脉破裂出血[J]. 中国临床医学, 2000, 7(2): 203-204 |
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| 作者姓名： | 施文娟 张顺财 |
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| 作者单位： | 上海医科大学中山医院消化科,200032 |
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| 摘 要： | 目的比较(善得定)和垂体后叶素治疗肝硬化食管静脉破裂出血的疗效、再出血等不良反应发生率.方法54例经急诊胃镜证实食管静脉破裂出血患者,随机分为善得定治疗组和垂体后叶素治疗组.结果善得定止血有效率84.00%,垂体后叶素为55.17%(P＜0.05);再出血善得定组8.00%,垂体后叶素组31.03%;善得定组不良反应发生率8.00%,垂体后叶素组34.48%(P＜0 01).结论善得定止血效果优于垂体后叶素,再出血发生率和不良反应发生率低于后者,是一种有效、安全的药物.
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| 关 键 词： | 善得定 垂体后叶素 食管静脉破裂出血 门脉高压 |
Clinical Study of Therapeutic Effect of Sandostatin and Pituitrin on Esophageal Variceal Hemorrhage |
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| Shi wenjuan,Zhang Shuncai. Clinical Study of Therapeutic Effect of Sandostatin and Pituitrin on Esophageal Variceal Hemorrhage[J]. Chinese Journal Of Clinical Medicine, 2000, 7(2): 203-204 |
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| Authors: | Shi wenjuan Zhang Shuncai |
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| Abstract: | Objective: To compare the therapeutic effects on variceal hemorrhage, rebleeding and side effect of octreotide (Sandostatin) and Pituitrin in the treatment of hemorrhage from esophageal varices. Materials and Methods: 54 cases of esophageal variceal hemorrhage confirmed by emergency gastroscopy were randomly divided into Sandostatin group and Pituitrin group. Results: Cessation of bleeding with Sandostatin therapy was 84. 00 % and that of Pituitrin was 55. 17 % (P < 0. 05). Rebleeding rate in group with Sandostatin was 8. 00 %, and that of Pituitrin was 31. 03 %. The rate of side effects with Sandostatin was 8. 00 %, and that of Pituitrin was 34. 48 % (P<0. 01). Conclusion: For esophageal variceal bleeding, Sandostatin is better than Pituitrin with higher cessation for bleeding, and lower incidence in rebleeding and side effect. Thus Sandostain is effective and safe in the treatment of esophageal variceal hemorrhage. |
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| Keywords: | Sandostatin Pituitrin Hemorrhage from esophageal varies Portal hypertention |
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