| 舒经玫瑰胶囊对小鼠原发性痛经血浆血栓素B2、6-酮-前列腺素F1α的影响 |
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| 引用本文： | 王昕,姚凝,刘健鸿,裴培田.舒经玫瑰胶囊对小鼠原发性痛经血浆血栓素B2、6-酮-前列腺素F1α的影响[J].中国中医药信息杂志,2008,15(6):41-42. |
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| 作者姓名： | 王昕 姚凝 刘健鸿 裴培田 |
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| 作者单位： | 甘肃中医学院,甘肃兰州730000 |
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| 基金项目： | 甘肃省教育厅资助（017Q-05） |
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| 摘 要： | 目的探讨舒经玫瑰胶囊对小鼠原发性痛经的保护作用。方法取体重24～26g未孕健康小鼠64只，随机分4组：生理盐水组、舒经玫瑰胶囊小剂量组（0．8g／25g）、舒经玫瑰胶囊大剂量组（8g／25g）、月月舒对照组（50mg／25g），以小鼠血浆中血栓素B2（TXB2）、6-酮-前列腺素F1α（6-Keto-PGF1α）为指标进行实验观察。结果舒经玫瑰胶囊对原发性痛经小鼠血浆中的6-Keto-PGF1α升高与TXB：的降低有显著作用（P〈0．01）。结论舒经玫瑰胶囊通过对TXB：及6-Keto—PGF1α含量的影响，对原发性痛经有保护作用。
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| 关 键 词： | 舒经玫瑰胶囊 原发性痛经:血栓素B2 6-酮-前列腺素F1α 小鼠 |
Effect of Red Rose Capsule for Releasing the Dysmenorrhea on Plasma Thromboxane B2 and 6-Keto-Prostaglandin F1α of Primary Dysmenorrhea Mice |
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| Institution: | WANG Xin, YAO Ning, LIU Jian-hong, et al (Gansu College of TCM, Lanzhou 730000, China) |
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| Abstract: | Objective To approach the protective actions of Red Rose Capsule for Releasing the Dysmenorrhea （RRC） on the mice of primary dysmenorrhea. Method Sixty four health rats with the similar menstrual cycle were divided into four groups - NS group, RRC low dose group, RRC high dose group and Yueyueshu group. The indexes of TXB2 and 6-Keto-PGF1α in plasma were observed. Result RRC had significant effect on increasing 6-Keto-PGF1α and decreasing TXB2 in plasma of primary dysmenorrhea mice. Conclusion RRC has protective action against primary dysmenorrhea by influencing the content of TXB2 and 6-Keto-PGF1α. |
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| Keywords: | Red Rose Capsule for Releasing the Dysmenorrhea primary dysmenorrheal TXB2 6-Keto-PGF1α mice |
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