| 剪切力对支架边缘内皮细胞的生物学影响 |
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| 引用本文： | 张步春综述,王安才审校. 剪切力对支架边缘内皮细胞的生物学影响[J]. 中国介入影像与治疗学, 2006, 3(6): 462-465 |
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| 作者姓名： | 张步春综述 王安才审校 |
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| 作者单位： | 皖南医学院弋矶山医院心血管内科,安徽,芜湖,241001 |
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| 基金项目： | 安徽省教育厅自然科学基金 |
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| 摘 要： | 经皮冠状动脉介入(PCI)是治疗冠心病重要手段,但其不可避免的会损伤内皮细胞,引起内皮细胞功能失调和/或结构损害。血管内皮细胞在冠状动脉支架再狭窄中扮演了非常重要角色,而一直作用于内皮的血液流动剪切力对内皮细胞形态及功能的改变起重要作用,本文就剪切力对支架边缘内皮细胞的生物学影响研究概况作一综述。
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| 关 键 词： | 剪切力 再狭窄 内皮细胞 |
| 文章编号： | 1672-8475（2006）06-0462-04 |
| 收稿时间： | 2006-05-16 |
| 修稿时间： | 2006-08-26 |
The effects of shear stress on endothelial cells biology at in-stent edge |
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| ZHANG Bu-chun and WANG An-cai. The effects of shear stress on endothelial cells biology at in-stent edge[J]. Chinese Journal of Interventional Imaging and Therapy, 2006, 3(6): 462-465 |
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| Authors: | ZHANG Bu-chun and WANG An-cai |
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| Affiliation: | Department of Cardiology, Yijishan Hospital of Wannan Medical College, Wuhu 241001, China |
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| Abstract: | Percutaneous coronary intervention is one of the most important means of treating heart diseases,but endothelial cells will be damaged,leading to endothelial dysfunction and/or structure impairment.Vascular endothelial cells play an importment role in the process of in-stent restenosis,and fluid shear stress acting on endothelial cells may also play a critical one in promoting endothelial cells morphology and function change.This article reviews recent researches aimed at the effects shear stress on endothelial cells biology at in-stent edge. |
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| Keywords: | Shear stress Restenosis Endothelial cells |
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