Acquired renal cystic disease in children and young adults on maintenance dialysis |
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Authors: | Tej K Mattoo Ira Greifer Pinhas Geva Adrian Spitzer |
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Institution: | (1) Division of Pediatric Nephrology, Albert Einstein College of Medicine, Rose F. Kennedy Center, 1410 Pelham Parkway South, Bronx, NY 10461, USA, US |
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Abstract: | Acquired renal cystic disease (ARCD) is a well-known complication of end-stage renal disease (ESRD). We studied 24 patients,
aged 8 – 27 years (mean 19.8±5.3 years), on chronic maintenance dialysis in our service. The duration of dialysis ranged between
13 and 192 months (mean 77.8±44.3 months). High-resolution ultrasonography revealed ARCD in 11 (45.8%) patients. No cysts
were seen in 7 (29.1%) patients and solitary cysts in one or both kidneys were seen in 6 (25%) patients. Renal malignancy
was diagnosed in 2 patients. One, 15 years old, had renal cell carcinoma after being on dialysis for 6 years. She did well
after bilateral nephrectomy, left salpingo-oophorectomy, and regional lymphadenectomy. The second patient, 23 years old, had
been on dialysis for 16 years when she developed renal oncocytoma. She died of congestive cardiomyopathy 6 months later. We
conclude that ARCD is common in children and young adults with ESRD. Neoplastic transformation, although rare, is a potential
complication. Annual follow-up with ultrasonography with selective use of computed tomography or magnetic resonance imaging
is advised.
Received July 29, 1996; received in revised form and accepted November 15, 1996 |
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Keywords: | : Dialysis Acquired renal cysts Renal malignancy Ultrasound |
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