| 急性心肌梗死患者血小板膜凝血酶敏感蛋白及糖蛋白Ⅳ的分布 |
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| 引用本文： | 李长运,董建增,曹剑英.急性心肌梗死患者血小板膜凝血酶敏感蛋白及糖蛋白Ⅳ的分布[J].郑州大学学报(医学版),2002,37(1):48-50. |
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| 作者姓名： | 李长运 董建增 曹剑英 |
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| 作者单位： | 1. 华中科技大学同济医学院附属协和医院心内科,武汉,430022
2. 郑州大学第一附属医院心内科,郑州,450052 |
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| 摘 要： | 目的:探讨急性心肌梗死(AMI)后患者血小板膜表面凝血酶敏感蛋白(TSP)及糖蛋白Ⅳ(GPⅣ)分布状况。方法:用流式细胞仪测定AMI患者(10例)静息状态时及凝血酶(0．1U/ml,0．5 U/ml)激活时,血小板膜表面TSP及 GPⅣ分布状况,并与正常人(12 名)进行比较。结果:AMI 12－72 h,静息血小板和激活血小板膜表面TSP及GPⅣ均明显高于正常人(P＜0．05,P＜0．001);AMI 168 h激活血小板膜 TSP及 GPⅣ高于正常人(P＜0．05,P＜0．01),静息血小板膜TSP及GPⅣ与正常人差异无显著性(P＞0.05)。AMI静息血小板和激活血小板膜TSP与GPⅣ呈显著正相关(r＝0.383,P＜0.001)。结论:AMI发生后72h内血小板活性及反应性明显增高,血小板反应性持续增高达AMI后168h。
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| 关 键 词： | 急性心肌梗死 糖蛋白类 凝血酶 血小板膜 |
| 修稿时间： | 2001年9月25日 |
Distribution of platelet membrane glycoprotein Ⅳ and thrombospondin in patients with acute myocardial infarction |
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| LI Changyun,DONG Jianzeng,CAO JianyingDeptartment of Cardiology,the Affiliated Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan Deptartment of Cardiology,the First Affiliated Hospital,Zhengzhou Un.Distribution of platelet membrane glycoprotein Ⅳ and thrombospondin in patients with acute myocardial infarction[J].Journal of Zhengzhou University: Med Sci,2002,37(1):48-50. |
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| Authors: | LI Changyun DONG Jianzeng CAO JianyingDeptartment of Cardiology the Affiliated Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Deptartment of Cardiology the First Affiliated Hospital Zhengzhou Un |
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| Institution: | LI Changyun,DONG Jianzeng,CAO JianyingDeptartment of Cardiology,the Affiliated Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022 Deptartment of Cardiology,the First Affiliated Hospital,Zhengzhou Un |
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| Abstract: | |
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| Keywords: | acute mvocardial infarction glycoproteins thrombin platelet |
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