| 神经节苷脂在急性重症颅脑损伤患者的治疗效果观察 |
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| 引用本文： | 胡新华,邢鸣,张岩松,刘翔,邹元杰,张锐,杨坤,刘宏毅.神经节苷脂在急性重症颅脑损伤患者的治疗效果观察[J].临床神经外科杂志,2009,6(2):79-80. |
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| 作者姓名： | 胡新华 邢鸣 张岩松 刘翔 邹元杰 张锐 杨坤 刘宏毅 |
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| 作者单位： | 1. 南京医科大学附属脑科医院神经外科,210029
2. 南京市高淳县医院神经外科 |
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| 摘 要： | 目的探讨神经节苷脂（GMI）对急性重症颅脑损伤患者的治疗效果及其药物的安全性。方法49例急性重症颅脑损伤患者随机分两组，常规治疗组24例，GM1治疗组25例。治疗14天后观察GCS及不良反应，3个月后观察GOS。结果GM1治疗组GCS评分和GOS评分明显比常规治疗组升高。结论早期应用GM1治疗急性重症颅脑损伤，可促进患者脑功能的恢复，改善预后，且副作用小，安全可靠。
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| 关 键 词： | 颅脑损伤 治疗 |
Therapeutic effects of GM1 in severe craniocerebral injury patients |
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| Institution: | HU Xin-hua, XING Ming, ZHANG Yan-song, et al. (Department of Neurosurgery, Brain Hospital Affiliated to Nanfing Medical University, Nanjing 210029, China) |
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| Abstract: | Objective To explore the therapeutic effeet of GMI in treating acute severe craniocerebral trauma patients and its safety. Methods randomly divided into treatment cases）. GCS and side effect were coma scale） were observed after 3 49 patients with acute severe craniocerebral trauma were group （25 cases）with GM1 and normal treatment group （24 observed in all patients 14 days after the treatment, GOS（glascow follow-up. Results The GCS and GOS（glascow outcome scale） significantly increased in the treatment group compared to the normal treatment group.Conclusion The early application of GM1 for acute severe craniocerebral trauma could promote recovery and improve the prognosis in patients. The side effect of GM1 is seldom. |
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| Keywords: | craniocerebral trauma treatment |
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