| 镇惊定志合剂治疗心胆气虚型失眠随机双盲对照试验研究 |
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| 引用本文： | 周洁,叶青,何静,袁灿兴.镇惊定志合剂治疗心胆气虚型失眠随机双盲对照试验研究[J].上海中医药大学学报,2017,31(5):40-43. |
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| 作者姓名： | 周洁 叶青 何静 袁灿兴 |
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| 作者单位： | 上海中医药大学附属龙华医院神经内科上海200032,上海中医药大学附属龙华医院神经内科上海200032,上海中医药大学附属龙华医院神经内科上海200032,上海中医药大学附属龙华医院神经内科上海200032 |
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| 基金项目： | 国家自然科学基金面上项目(81673726)；上海市进一步加快中医药事业发展三年行动计划项目(ZY3-JSFC-2-1007)；上海市卫计委杏林新星人才计划项目(ZY3-RCPY-2-2005) |
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| 摘 要： | 目的:观察镇惊定志合剂治疗心胆气虚型失眠的临床疗效。方法:采用随机双盲安慰剂对照的研究方法,以心胆气虚型失眠患者为研究对象;将72例患者随机分为治疗组(36例)服用镇惊定志合剂和对照组(36例)服用镇惊定志合剂安慰剂,疗程共4周。观察治疗前后两组患者匹兹堡睡眠指数量表(PSQI)积分、SPIEGEL量表积分、中医证候分级量化表积分及CPC睡眠质量测评结果变化情况。结果:治疗后,治疗组PSQI量表积分、SPIEGEL量表积分、中医证候分级量化表积分均较治疗前明显降低(P0.05),且低于对照组(P0.05);对照组各积分降低无显著差异(P0.05)。治疗后,治疗组心肺耦合技术(CPC)睡眠监测结果明显改善(P0.05),对照组改善不明显(P0.05),治疗组的改善明显优于对照组(P0.05)。结论:镇惊定志合剂治疗心胆气虚型失眠疗效良好,可改善临床症状和提高睡眠质量。
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| 关 键 词： | 失眠 心胆气虚型 镇惊定志合剂 随机双盲对照 |
| 收稿时间： | 2017/4/26 0:00:00 |
Efficacy of Zhenjing Dingzhi Mixture in the Treatment of Insomnia with Qi Deficiency of Heart and Gallbladder:A Randomized, Double-blind and Controlled Trial |
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| ZHOU Jie,YE Qing,HE Jing and YUAN Can-xing.Efficacy of Zhenjing Dingzhi Mixture in the Treatment of Insomnia with Qi Deficiency of Heart and Gallbladder:A Randomized, Double-blind and Controlled Trial[J].Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai,2017,31(5):40-43. |
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| Authors: | ZHOU Jie YE Qing HE Jing and YUAN Can-xing |
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| Institution: | Department of Neurology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,200032,Department of Neurology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,200032,Department of Neurology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,200032 and Department of Neurology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai,200032 |
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