| 金莲花抗菌有效成分 |
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| 引用本文： | 李占林,李丹毅,吴 瑛,华会明. 金莲花抗菌有效成分[J]. 沈阳药科大学学报, 2008, 25(8): 627-629 |
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| 作者姓名： | 李占林 李丹毅 吴 瑛 华会明 |
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| 作者单位： | [1]沈阳药科大学中药学院,辽宁沈阳110016 [2]辽宁百草医药有限公司,辽宁沈阳110005 |
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| 摘 要： | 目的对金莲花水提物中具有体外抗菌活性的化学成分进行研究。方法通过硅胶柱色谱、Sephadex LH-20柱色谱等手段进行分离,利用理化性质和波谱数据分析鉴定结构。结果得到7个化合物,分别鉴定为:藜芦酸(1)、苯甲酸(2)、(R)-10,16-二羟基十六烷酸(3)、芹菜素(4)、木犀草素(5)、鼠尾草素(6)和槲皮素(7)。结论化合物2-4为首次从该属植物中分离得到。
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| 关 键 词： | 金莲花 抗菌活性 有机酸 黄酮 |
| 收稿时间： | 2007-10-23 |
Antibacterial constituents from the flowers of Trollius chinensis Bunge |
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| LI Zhan-lin,LI Dan-yi,WU Ying,HUA Hui-ming. Antibacterial constituents from the flowers of Trollius chinensis Bunge[J]. Journal of Shenyang Pharmaceutical University, 2008, 25(8): 627-629 |
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| Authors: | LI Zhan-lin LI Dan-yi WU Ying HUA Hui-ming |
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| Affiliation: | 1.School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China; 2.Liaoning Baicao Pharmaceutical Co.,Ltd, Shenyang 110005,China |
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| Abstract: | Objective To study the antibacterial constituents from the water extract of the flowers of Trollius chinensis Bunge. Methods The constituents were isolated by repeated column chromatography on silica gel and Sephadex LH-20 and identified by physico-chemical characteristics and spectroscopic analysis. Results Seven compounds were isolated from the CHCl3 and ethyl acetate extracts, which were identified as: veratic acid (1), benzoic acid (2), (R)-10, 16-dihydroxyhexadecanoic acid (3), apigenin (4), luteolin (5), salvigenin (6), and quercetin (7). Conclusions Compounds 2-4 were isolated from this genus for the first time. |
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| Keywords: | Trollius chinensis Bunge')" >Trollius chinensis Bunge antibacterial activity organic acid flavonoid |
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