临沂市已婚育龄夫妇不孕症病因构成研究

目的分析临沂市已婚育龄夫妇不孕症病因总体构成情况并排列病因顺位,指导不孕症病因诊断和疾病预防。方法研究2013年1月-2014年7月在临沂市妇幼保健院生殖医学中心就诊的不孕症患者病历资料。统计分析各类病因构成比,排列病因顺位。比较原发不孕和继发不孕病因构成比有何不同,分析疾病成因。结果 3195对不孕夫妇中,单纯女方异常者占49.20%;单纯男方异常占15.65%;双方均异常者占17.97%。继发不孕占54.05%,多于原发不孕的45.95%。女性不孕主要病因构成及顺位依次是：输卵管及盆腔因素（36.65%）;排卵障碍（33.62%）;子宫因素（13.08%）;免疫因素（10.14%）;子宫内膜异位症（6.32%）。男性不育病因构成及顺位依次是：特发性弱精子症（7.51%）;精索静脉曲张（7.51%）;男性副性腺炎症（7.39%）;免疫学病因（5.79%）;特发性少精子症（5.23%）。原发和继发病因构成有差异。结论临沂市已婚育龄夫妇不孕症病因主要是输卵管病变,排卵障碍和男性精液质量异常。继发不孕多于原发不孕,原发不孕以排卵障碍最为常见;继发不孕首要病因应考虑输卵管因素。

STUDY ON THE COMPOSITION OF INFERTILITY ETIOLOGY OF MARRIED COUPLES OF CHILD-BEARING AGE IN LINYICITY

Objective To investigate the overall composition and the sequence of infertility causes of married couples of child-bearing age in Linyi for guiding the infertility diagnosis and disease prevention.Methods From January 2013 to July 2014,3195 patients of infertility in reproductive medical center of Linyi Women and Children Health Care Hospital had been set up a complete standardized diagnosis and treatment medical records for investigating and analyzing.Statistical analysis and sequencing of all kinds of causes was made.Comparing the differences between the primary and secondary infertility and analyzing the causes of infertility.Results Of the 3195 infertile couples,pure female abnormal accounted for 49.20%;Simple man abnormalities was 15.65%;Both sides was abnormal accounted for 17.97%.Secondary infertility accounted for 54.05%,and primary infertility was more than 45.95%.Main causes of female infertility composition and the sequence is in turn that fallopian tube and pelvic factors was 36.65%;Ovulationdisorders was 33.62%;Uterine factors was 13.08%;Immune factors was 10.14%;Endometriosis was 6.32%.The sequence of the male infertility etiology was in turn that idiopathic weak sperm disease was 7.51%;Varicocele was 7.51%;Men＇s deputy sex gland inflammation was 7.39%;Immunological etiology was 5.79%）;Sperm idiopathic was 5.23%.There are differences between the primary and secondary infertility.Conclusion The infertility etiology of married couples of child-bearing age in Linyi was mainly for Fallopian tube factors,abnormal ovulation and male semen quality.Secondary infertility patients are more than that of primary infertility.The primary infertility was mainly for ovulation disorders and Secondary infertility are mainly for fallopian tube diseases.