高强度聚焦超声治疗子宫肌瘤及子宫腺肌病临床研究

目的评价高强度聚焦超声(HIFU)治疗子宫肌瘤、子宫腺肌病的临床疗效。方法 86例子宫肌瘤患者148个病灶、34例子宫腺肌病34个病灶行HIFU治疗,治疗后1、3、6个月随访,评价病灶的超声及MRI影像学变化及患者的临床症状改善情况。结果彩超及MRI影像学随访发现86例子宫肌瘤148个病灶治疗后第1个月肌瘤体积平均缩小35%,第3个月缩小59%,第6个月缩小72%;67例经量增多的子宫肌瘤及腺肌病患者,61例在治疗后6个月经量明显减少,有效率为91.0%;34例痛经的子宫腺肌病患者,32例在治疗后随访的6个月内痛经消失或减轻,有效率为94.1%。结论 HIFU治疗子宫肌瘤、子宫腺肌病具有显著的临床疗效,且无明显并发症、副反应。

Clinical study on curing uterine fibroids and adenomyosis with high intensity focused ultrasound

Objective To evaluate the clinical efficacy and safety of HIFU ablation for uterine fibroids and adenomyosis.Methods 86 patients with 148 uterine fibroids and 34 patients with 34 adenomyosis were treated with HIFU.Color Doppler flow imaging(CDFI) and MRI were performed at 1,3,6 months after HIFU.The clinical symptoms were also evaluated.Results Follow-up MRI and CDFI demonstrated that the fibroid volume reduced by an average of 35% in the first month,59% at the 3 months,72% at the 6 months after HIFU.61 of 67(91%) patients with heavy and prolonged menstrual flow had symptoms relieved after HIFU treatment.32 of 34(94.1%) women with dysmenorrhea had the pain sustained relieved 6 months after HIFU treatment.No major side effects were observed during the follow-up period.Conclusion HIFU has obvious clinic effect on uterine fibroids and adenamyosis,and correlative syndrome and side-offect haven’t occurred apparertly.