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系统性红斑狼疮小鼠模型的研究近况
引用本文:任文英. 系统性红斑狼疮小鼠模型的研究近况[J]. 免疫学杂志, 2003, 0(Z1)
作者姓名:任文英
作者单位:北京中医药大学 北京
摘    要:系统性红斑狼疮(SLE)小鼠模型的研究对揭示SLE发病原因、发病机制及探索治疗方法具有重要价值。本文介绍了几种SLE小鼠模型的研究近况,以BXSB小鼠为主,同时介绍(NZBxNZW)F1、MRL/lpr及诱导的SLE样小鼠,从小鼠的品系来源、发病特点、免疫学特征、相关基因以及治疗状况等几个方面进行了综述。

关 键 词:系统性红斑狼疮  小鼠模型  免疫学  相关基因

Recent advances on the study of systemic lupus erythematosus models
REN Wen-ying. Recent advances on the study of systemic lupus erythematosus models[J]. Immunological Journal, 2003, 0(Z1)
Authors:REN Wen-ying
Abstract:The study on systemic lupus erythematosus (SLE) models is very important for revealing etiology and pathogenesis and exploring the plan on treatment. Several SLE models, including BXSB mice,(NZBxNZW) F1 mice, MRL/lpr mice and induced SLE mice were introduced in this review. The paper also reviewed the source of mice, the character of the disease, immunology, related gene and treatment, and so on.
Keywords:Systemic lupus erythematosus  Mice model  Immunology  Related gene
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