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| 诊断超声对大鼠孕期胎盘组织中NO的阶段性影响 | |
| 引用本文： | 梁建涛,霍丽蓉,史治山,刘晋敏,刘望彭. 诊断超声对大鼠孕期胎盘组织中NO的阶段性影响[J]. 山西医科大学学报, 2001, 32(6): 487-488 |
| 作者姓名： | 梁建涛 霍丽蓉 史治山 刘晋敏 刘望彭 |
| 作者单位： | 1. 山西医科大学解剖学教研室, 2. 山西医科大学微生物与免疫学教研室, 3. 山西介休市人民医院, 4. 山西医科大学公共卫生学院, 5. 山西医科大学第一临床医学院, |
| 摘 要： | 目的 通过检测大鼠孕早期超声辐照后其胎盘组织中一氧化氮合酶（nitric oxide synthetase,NOS）活性及一氧化氮（nitic oxide,NO）含量的阶段变化，旨在为临床孕早期超声诊断的安全性评价提供一定的实验依据。方法 将孕鼠分期采用生化技术检测其胎盘组织中相关生化指标的变化。结果 NOS活性与NO含量测定，孕早期实验组均明显低于对照组（P＜0．01），中晚期与对照组相比已无显著性差异。结论 孕早期接受一定剂量的超声辐射可使NO含量和NOS活性下降。 |
| 关 键 词： | 一氧化氮合酶 一氧化氮 胎盘组织 超声诊断 动物实验 妊娠 |
| 文章编号： | 1007-6611(2001)06-0487-02 |
Effect of diagnostic ultrasound on changes of NO of rat placenta in pregnancy |
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| LIANG Jian tao,HUO Li rong,SHI Zhi shan,et al. Effect of diagnostic ultrasound on changes of NO of rat placenta in pregnancy[J]. Journal of Shanxi Medical University, 2001, 32(6): 487-488 | |
| Authors: | LIANG Jian tao HUO Li rong SHI Zhi shan et al |
| Abstract: | Objective To assess the changes of NOS and NO levels after exposing ultrasonic diagnostic dosage to early pregnancy rats. Methods Biochemical technique was adopted to study the changes of NO and NOS metabolism. Results The NOS and NO levels were significantly lower in treated groups than in control group ( P <0 01) in early pregnancy, however, in the middle and later pregnancy there was no difference between 2 groups. Conclusion Diagnostic ultrasound in early pregnancy can make NO and NOS levels decrease. |
| Keywords: | ultrasonography nitric oxide synthetase nitric oxide |
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