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前列腺癌早期诊断肿瘤标志物的研究进展
引用本文:刘志明,李泽惠,李志鹏.前列腺癌早期诊断肿瘤标志物的研究进展[J].医学综述,2009,15(1):55-57.
作者姓名:刘志明  李泽惠  李志鹏
作者单位:昆明医学院第二附属医院泌肾外科,昆明,650101
基金项目:云南省教育厅科学研究基金 
摘    要:目前,前列腺癌的早期诊断方法主要是通过前列腺特异性抗原筛查,但前列腺特异抗原的特异性低。近年来,不断有学者提出各种肿瘤标志物,试图寻找敏感性、特异性更高的生物标志物。现就近年研究中较新、较有前景的几种肿瘤生物标志物(α-甲基-辅酶A消旋酶、Survivin蛋白、胸腺素β15、核基质蛋白)予以综述。

关 键 词:前列腺癌  α-甲基-辅酶A消旋酶  survivin蛋白  胸腺素β15  核基质蛋白  肿瘤标志物

The Progress of Carcinoma of Prostate Early Diagnosis Tumor Markers
LIU Zhi-ming,LI Ze-hui,LI Zhi-peng.The Progress of Carcinoma of Prostate Early Diagnosis Tumor Markers[J].Medical Recapitulate,2009,15(1):55-57.
Authors:LIU Zhi-ming  LI Ze-hui  LI Zhi-peng
Institution:LIU Zhi-ming,Ll Ze-hui, LI Zhi-peng. ( Department of Urinary and Kidney Surgeory, the Second Affiliated Hospital of Kunming Medical College, Kunming 650101, China )
Abstract:Currently,Prostate-specific antigen screening is the main method for early diagnosis of prostate cancer, but the specificity of PSA is low. In recent years, a variety of tumor markers have been raising to find out the biology, marker with higher sensitivity and specificity. This article is intented to make a review about some of more promising tumor biomarkers such as α-methyl-coenzyme A raeemase, Survivin protein, Thymosin β15 ,nuclear matrix protein.
Keywords:Prostate cancer  α -methylacy-coenzyme A racemase  Survivin  Thymosinβ15  Nuclear matrix proteins  Tumor markers
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