68例肺癌骨转移部位的分析

目的　探讨肺癌骨转移的临床特点。方法　临床资料回顾性分析。结果　肺癌骨转移多发者占 81.8% ,单发者 18.2 %。肺癌患者中腺癌发生骨转移占 6 5 .75 % ,鳞癌 34.2 1% ,小细胞未分化癌 38.89%。骨转移的部位胸部 6 6 .18% ,脊柱 5 2 .94% ,骨盆 42 .6 4% ,四肢 30 .88% ,头颅 2 0 .5 9%。腺癌以肋骨、脊柱、骨盆转移为主 ,鳞癌及小细胞肺癌以胸部和脊柱转移为主。X线、CT、MRI检查提示骨转移以溶骨性骨破坏的占 82 .35 % ,成骨性骨破坏11.76 % ,混合性损害 5 .88%。结论　肺癌骨转移以多发性、溶骨性骨破坏为特征。腺癌骨转移发生率最高 ,其次为小细胞癌及鳞癌。

Clinical analysis for the metastasis sites of 68 cases with lung cancer

Objective To describe features of osseous metastases in patients with lung cancer.Methods 68 cases were retrospectively analysed. Results 81.8% patients had multiple osseous metastases and 18.2% had single metastasis.In all the 68 cases,65.75% was adenocarcinoma,34.21% squamous carcinoma,38.89% small cell lung cancer. The frequencies of metastasis sites were as follows,eg, ribs(66.18%),thoracic and lumber vertebrae(52.94%),pelvis (42.64%),limbs(30.88%).Adenocarcinoma was prone to metastasize to thoracic vertebrae and pelvis,squamous carcinoma and small cell lung cancer to ribs and thoracic vertebrae . In patients undergoing X-ray?CT?MRI examination,82.35% had osteolytic damages,11.76% osteoblastic damages,5.88% mixed damages.Conclusions Osseous metastasis in patients with lung cancer is characterized by multiple osteolytic damages. Adenocarcinoma is one of the most common types of lung cancer that causes osseous metastasis.=