中药辅助抗菌药治疗小儿肠系膜淋巴结炎的Meta分析

目的 系统评价中药辅助抗菌药治疗小儿肠系膜淋巴结炎的疗效。方法 检索1980-2016年中国期刊全文数据库（CNKI）、万方数字化期刊全文库、中文科技期刊全文数据库（VIP）、PubMed、Medline数据库中关于中药辅助抗菌药治疗小儿肠系膜淋巴结炎的随机对照研究（RCT），依据纳入和排除标准筛选文献，采用Jadad评分进行评价，运用RevMan 5.3软件进行Meta分析。结果 共纳入34篇临床RCT，3 504例患者。Meta分析结果显示试验组在有效率、治愈率、主要症状和体征缓解时间、肠系膜淋巴结恢复、复发率方面均优于对照组，两者差异具有统计学意义。结论 中药辅助抗菌药物治疗小儿肠系膜淋巴结炎疗效优于单独使用抗菌药。

Meta-analysis of effectiveness of Chinese materia medica as adjuvant therapy of antibacterial for pediatric mesenteric lymphadenitis

Objective To assess the effectiveness of Chinese materia medica(CMM) as adjuvant therapy of antibacterial for pediatric mesenteric lymphadenitis. Methods Retrieved RCTresearch of CMM as adjuvant therapy of antibacterial for pediatric mesenteric lymphadenitis from CNKI, Wanfang, VIP,PubMed, andMedline database from 1980 to 2016. Literatures were selected according to the inclusion and exclusion crteria, Jadad scores method was used to evaluate the literatures and meta-analysis was performed by RevMan 5.3. Results A total of 34 randomized controlled trials were included. Meta-analysis showed that the trial group was superior to the control group in terms of efficiency, cure rate, remission time of main symptoms, mesenteric lymph node recovery, and recurrence rate, there was statistical difference. Conclusions CMM as adjuvant therapy of antibacterial for pediatric mesenteric lymphadenitis is more effective than the use of antibacterial alone.