冬虫夏草对肾衰患者细胞氨基酸代谢的影响

目的 研究冬虫夏草（虫草）对曼性肾功能衰竭（ＣＲＦ）患者细胞内外氨基酸代谢的影响。方法 采且ＬＫＢ－４４００型氨基酸自动分析仪测定１０例ＣＲＦ患者服用虫草前后的血浆、红细胞、骨骼肌细胞内的游离氨基酸浓度。结果 ＣＲＦ患者服用虫草后血浆中亮氨酸、异这氨酸、苏氨酸、赖氨酸、胱到、酷氨酸浓度和红细胞中酷氨酸、谷氨酸浓度接近正常，１例骨骼肌标本苏氨酸、赖氨酸浓度接近正常；而细胞内外缬氨酸浓度仍显著降低。结

The Influence of Cordyceps Sinensis on the Extracellular and Intracellular Free Amino Acid Levels in Patients with CRF

Objective To study the Cordyceps Sinensis acting on the metabolism of intrace llular and extracellular amino acids in patients with CRF. Methods We observed ten patients with CRF, compared the free amino acid concentrations in plasma, erthrocytes and skeletal muscle before and after Cordyceps Sinensis treatment by the amino acid automatic analytical instrument. Results After the CRF group took Cordyceps Sinensis, the Leu, Ile, Thr, Lys, Cys, Tyr concentrations in plasma and Tyr, Glu in erythrocytes approached the normal levels. In one sample of skeletal muscle, the Thr, Lys concentrations approached the normal, whereas both the intracellular and extracellular Val concentrations were still decreased remarkably as compared with the normal controls. Conclusion In patinets with CRF, Cordyceps Sinensis can improve the metabolic disorder notably, increase the dropped free amino acids in varying degrees, but couldn't correct completely the disturbance.