骨基质明胶复合自体红骨髓及同种异体骨修复骨缺损

目的:评价骨基质明胶复合自体红骨髓及同种异体骨联合移植修复骨缺损的疗效。方法:76例良性骨肿瘤和瘤样病损患者,彻底刮除病灶或作肿瘤骨段切除,并对瘤壁作灭活处理,以同种异体骨作支架,周围填充骨基质明胶和自体红骨髓复合物,术后观察机体反应及骨缺损修复情况。结果:术后机体无明显免疫排斥反应,无1例发生感染,所有病例随访时间为5～16个月,X线显示新骨形成时间为术后1.5～4月,完全骨化的时间为术后5～9月,骨缺损骨性愈合74例,并获得较好的关节功能,肿瘤复发2例。结论:骨基质明胶、自体红骨髓、同种异体骨复合物能有效修复骨缺损,有广泛的临床应用前景。

Bone Matrix Gelatin Combined with Autologuous Red Bone Marrow and Allograft for Treatment of Bone Defects

Objective:To investigate the efficacy of the combined of grafting materials composed of homologuous bone matrix gelatin (BMG) and autologuous red bone marrow and allograft in repairing bony cavity defect produced by benign bone tumor. Methods:Seventy-six patients with benign tumor or phymatoid lesion were studied,all cases were treated with curettage or segmental resection, the post-operative bony defect sites were filled with the combined of grafting materials. Results: All cases were followed up from 5 months to 16 months,74 cases achieved a solid union with good joint function without complication and obvious immunologic rejection. Conclusion: It suggests that the combined of grafting materials can efficiently repair bony defect and has great potential for clinical use.