| 右旋酮洛芬壳聚糖凝胶剂的制备与质量控制 |
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| 引用本文： | 王志朝,刘祖雄.右旋酮洛芬壳聚糖凝胶剂的制备与质量控制[J].中国药业,2005,14(6):55-56. |
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| 作者姓名： | 王志朝 刘祖雄 |
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| 作者单位： | 中国人民解放军广州军区武汉总医院药剂科,湖北,武汉,430070 |
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| 摘 要： | 目的:制备右旋酮洛芬壳聚糖凝胶剂并建立质量控制方法.方法:以壳聚糖、卡波普为凝胶材料制备右旋酮洛芬壳聚糖凝胶剂,采用紫外分光光度法测定右旋酮洛芬含量,采用留样观察法进行稳定性考察.结果:该凝胶剂制备工艺简单,含量测定方法可靠,质量稳定.结论:该制剂符合<中国药典(二部)>凝胶剂项下有关规定.
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| 关 键 词： | 右旋酮洛芬 壳聚糖 凝胶剂 制备工艺 |
| 文章编号： | 1006-4931(2005)06-0055-01 |
| 修稿时间： | 2004年8月4日 |
Preparation and Quality Control of Dexketoprofen Chitosan Gel |
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| Wang Zhichao,Liu Zuxiong.Preparation and Quality Control of Dexketoprofen Chitosan Gel[J].China Pharmaceuticals,2005,14(6):55-56. |
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| Authors: | Wang Zhichao Liu Zuxiong |
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| Abstract: | Objective:To study the preparation of dexketoprofen chitosan gel,and to set up method of quality control.Methods:To study the preparation dexketoprofen chitosan gel with chitosan and carbopol for gel material.To determine content of dexketoprofen with UV-spectrophotometry.Its stability property was examined by remaining sample and observing methods.Results:Preparation technology is simple,and the content measurement method is feasible,and quality is stable.Conclusion:It is accordant with condition of gel in China pharmacopoeia 2000 year edition. |
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| Keywords: | dexketoprofen chitosan gel preparation technologychnologicai |
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