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BCG和IL—2膀胱内灌注预防膀胱癌术后复发的临床观察
引用本文:潘正跃,李国荣,等.BCG和IL—2膀胱内灌注预防膀胱癌术后复发的临床观察[J].江西医学院学报,1998,38(3):67-68.
作者姓名:潘正跃  李国荣
作者单位:南昌第二附属医院泌尿外科!南昌,330006,南昌第二附属医院泌尿外科!南昌,330006,南昌第二附属医院泌尿外科!南昌,330006,南昌第二附属医院泌尿外科!南昌,330006
摘    要:为了降低膀胱癌术后复发率,联合应用BCG和IL-2膀胱内灌注32例。随访6个月~7年6个月,平均48个月。手术后1年内复发1例(3.1%),2年内复发5例(15.6%),5年内复发7例(21.9%)。结果表明,联合应用BCG和IL-2膀胱内灌注可以增强免疫治疗效果,明显地降低膀胱癌术后的复发率,同时可以减少BCG用量过大所引起的并发症。

关 键 词:膀胱肿瘤    灌注法

Intravesical Instillation of BCG and IL-2 in the Prevention of Postoperative Recurrence of Bladder Tumor
Pan Zhengyao, Li Guorong, Ge Gen, Huang Guohua.Intravesical Instillation of BCG and IL-2 in the Prevention of Postoperative Recurrence of Bladder Tumor[J].Acta Academiae Medicinae Jiangxi,1998,38(3):67-68.
Authors:Pan Zhengyao  Li Guorong  Ge Gen  Huang Guohua
Abstract:To reduce postoperative recurrence rate of bladder cancer, intravesical instillation of acombination of 100000 units of IL-2 and 100 mg of BCG was given postoperatively to 32 patients with bladder cancer. Postoperative recurrence rate of bladder cancer in 1 year was 3.1% (1/32);in 2 years, 15. 6% (5/32) and in 5 years 21. 9% (7/32). BCG together with IL-2Is recommended for intravesical instillation to strengthen the effect of immunotherapy, tolower the postoperative recurrence rate of bladder cancer and to reduce complications causedby over dose of BCG.
Keywords:bladder neoplasms  carcinoma  intravesical instillation  
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