组织多普勒成像在评价宫内发育迟缓胎儿心功能中的应用

目的：应用组织多普勒成像(tissue Doppler imaging，TDI)技术评估宫内发育迟缓(intrauterine growth retardation，IUGR)胎儿心功能情况。方法：测量IUGR组与对照组胎儿房室瓣口血流速度(E，A)，瓣环运动速度(E′， A′，S′)，等容收缩时间(isovolumetric contraction time，ICT)，射血时间(ejection time，ET)，等容舒张时间(isovolumetric relaxation time，IRT)；计算E/A，E′/A′，E/E′，E/(E′×S′)及心肌做功指数(myocardial performance index，MPI)。结果： IUGR胎儿E，A，E/A较对照组有减低趋势，但差异无统计学意义(P>0.05)；E′，A′，S′，E′/A′较对照组明显减低 (P<0.05)；E/E′，E/(E′×S′)，MPI较对照组增高(P<0.05)。结论： IUGR胎儿心脏舒张、收缩功能较正常降低。

Tissue Doppler imaging in the evaluation of cardiac function in fetuses with intrauterine growth retardation

Objective: To evaluate the cardiac function of fetuses with intrauterine growth retardation (IUGR) by using tissue Doppler imaging (TDI). Methods: Peak velocity in early (E) and late (A) diastole were measured by pulsed-wave Doppler, and the peak annular velocities in systole (S′), early (E′) and late (A′) diastole were measured by TDI. Isovolumetric contraction time (ICT), ejection time (ET), isovolumetric relaxation time (IRT) were recorded. The ratios E/A, E′/A′, E/E′, E/(E′×S′) and myocardial performance index (MPI) were calculated. Results: Compared with the control group, E′, A′, S′ and E′/A′ were obviously lower (P<0.05) while E/E′, E/(E′×S′) and MPI were obviously higher (P<0.05) in the IUGR group; although E, A and E/A were slight lower in the IUGR group, the change was not significant (P>0.05). Conclusion: Both diastolic and systolic heart function were jeopardized in IUGR fetuses.