急性脑梗死D-二聚体测定的临床研究

目的通过测定急性脑梗死D-二聚体(D-Dimer)含量的变化,为进一步了解急性脑梗死病理生理机制、病程判断及疗效观察提供试验依据。方法对30例急性脑梗死患者和20例正常人用Elisa法测定血浆D-二聚体(D-Dimer)含量。结果急性脑梗死患者急性期血浆D-二聚体含量较正常人明显升高(P<0.01),恢复期下降,急性期和恢复期比较有显著差异(P<0.01)。结论提示急性脑梗死患者急性期呈高凝状态的表现,血浆D-二聚体动态测定可作为急性脑梗死病程判断及疗效观察的有用的指标。

Plasma D-Dimer measuring of the Acute Cerebral Infarction Patients

Objective Find out the change of plasma D-Dimer standerd in acute cerebral infarction patients, to provide the experimental foundation for farther research of pathology, physiology pathological process judgment and effecitent.Methods To measure the plasma D-Dimer standerd by Elisa in 30 acute cerebral infarction patients and 20 normal ones.Results The plasma D-Dimer standerd of acute cerebral infarction patients in acute period has higher than normal ones and reduced/dropped in resume period, it was varied greatly at ratio to compare acute period and resume period.Conclusion The results indicated that acute cerebral infarction was the manifestation of hyper coagulation.plasma D-Dimer measuring was valueble for pathological process judgment and effectient observation in acute cerebral infarction patients.