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脑胶质瘤病
引用本文:张义,吴劲松,潘力,张福林,陈宏,邬剑军. 脑胶质瘤病[J]. 中华神经外科杂志, 2001, 17(1): 7-10
作者姓名:张义  吴劲松  潘力  张福林  陈宏  邬剑军
作者单位:1. 上海医科大学华山医院神经外科
2. 上海医科大学华山医院神经病理科
3. 上海医科大学华山医院神经内科
摘    要:目的 探讨脑胶质瘤病(GC)的诊断和治疗。方法 对本院神经外科1982-1997年间收治的13例GC进行回顾性研究。结果:GC临床表现以头痛(11/13)和癫痫(4/13)为常见,后期多出现严惩颅高压片象。病灶弥漫性生长6例,多发性生长7例,9例行开颅手术,3例行立体定向穿刺活检,1例行尸检,病理诊断:星形胶质瘤I级7例,星形胶质瘤I-II级2例,星形胶质瘤II级2例,少枝胶质瘤I级1例,少枝-星形混合胶质瘤II级1例,平均生存期为5.75月,结论 讨论了GC的发生,临床表现,影像学特点,病理特点,治疗方法以及预后。

关 键 词:脑肿瘤 胶质瘤 立体定向术 治疗

Gliomatosis cerebri
Abstract:Objective To characterize the diagnosis and treatment of gliomatosis cerebri (GC). Methods Clinical studies of 13 patients with GC (1982-1997) were reviewed retrospectively. Results The main clinical presentation of the 13 cases included headache (11/13), seizure (4/13), and sign of evaluated intracranial pressure later. The tumor involved at least 2 lobes of brain in all patients, in which diffused infiltration in 6 cases and multiple lesions in 7 cases. Nine cases underwent partially surgical removal of the tumor lesions and 3 cases underwent stereotactic biopsy. The Pathologic diagnosis were low-grade astrocytoma (grade Ⅰ~Ⅱ) in 11, grade I oligodendrocytoma in 1, and both mixture in 1. The mean lifetime was 5.75 months. Conclusions The tumorigenesis, clinical presentation, characters of CT and MRI images, pathological classification, therapy and prognosis of GC were discussed.
Keywords:Gliomatosis cerebri Stereotactic biopsy Diagnosis
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