机关中青年干部高血压患病及相关危险因素分析

目的了解机关中青年(年龄60岁)干部高血压发病率及与相关危险因素关系。方法入选2012年3月~5月在武警总医院健康医学中心进行体检的机关中青年干部538例,其中男性445例,女性93例。将是否患高血压作为因变量,以性别、年龄、体质指数(BMI)、腰围(WC)、空腹血糖(FPG)、血尿酸(UA)、血脂指标等做为自变量,进行单因素分析及多因素非条件Logistic回归分析。结果机关中青年干部高血压患病率为17.3%。与血压正常组相比,高血压患者男性构成比,BMI、WC、三酰甘油(TG)、低密度脂蛋白(LDL-C)、UA及餐后2 h血糖(2h PBG)明显升高,差异有显著统计学意义(P0.01);高血压组合并超重/肥胖、糖耐量异常、高胆固醇(TC)血症、高UA血症比例明显增高(P0.05)。多因素非条件Logistic回归分析结果表明,男性(OR=4.24,95%CI:1.47~6.36)、BMI(OR=5.16,95%CI:1.36~5.76),2h PBG(OR=2.73,95%CI:1.31~5.69)、TC(OR=2.03,95%CI:1.02~7.31)是高血压的独立危险因素。结论机关中青年干部高血压患病率较高,男性、BMI、TC及2h PBG是高血压的独立危险因素。

Incidence of hypertension and relative risk factors in office young and middle-aged cadres

Objective To get to know the incidence of hypertension and relationship between it and relative risk factors in office young and middle-aged cadres （aged〈60）. Methods The office young and middle-aged cadres （n=538, male 445 and female 93） were chosen from Mar. to May in 2012. Taking hypertension as dependent variable and sex, age, BMI, waist circumference （WC）, fasting plasma glucose （FPG）, uric acid （UA） and blood fat indexes as independent variable, univariate analysis and multivariate non-conditional Logistic regression analysis were conducted. Results The incidence of hypertension was 17.3%in office young and middle-aged cadres. Compared with normal group, the ratio of male patients, BMI, WC, TG, LDL-C, UA and 2hPBG increased significantly in hypertension group （P〈0.01）. The percentage of patients with complicating overweight/obesity, impaired glucose tolerance, hypercholesteremia and hyperuricacidemia increased significantly in hypertension group （P〈0.05）. The results of multivariate non-conditional Logistic regression analysis showed that male （OR=4.24, 95%CI：1.47-6.36）, BMI （OR=5.16, 95%CI：1.36-5.76）, 2hPBG （OR=2.73, 95%CI：1.31-5.69）, and TC （OR=2.03, 95%CI：1.02-7.31） were independent risk factors of hypertension. Conclusion The incidence of hypertension is higher in office young and middle-aged cadres, and male, BMI, TC and 2hPBG are independent risk factors of hypertension.