不同年龄重症冠心病患者高敏C反应蛋白、应激性血糖及糖化血红蛋白的比较 |
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引用本文: | 鲁琳,;任平香,;于大勇,;卢新,;赵建玲. 不同年龄重症冠心病患者高敏C反应蛋白、应激性血糖及糖化血红蛋白的比较[J]. 中国循证心血管医学杂志, 2014, 0(4): 428-429 |
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作者姓名: | 鲁琳, 任平香, 于大勇, 卢新, 赵建玲 |
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作者单位: | [1]唐山市工人医院神经内一科,唐山063000; [2]唐山市丰润区人民医院内分泌科;,唐山063000; [3]唐山市丰润区人民医院ICU科;,唐山063000; [4]唐山市丰润区人民医院神经内三科;,唐山063000; [5]唐山市丰润区燕山医院内科,唐山063000; |
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摘 要: | 目的探讨不同年龄重症冠状动脉粥样硬化性心脏病(冠心病)患者高敏C反应蛋白(hsCRP)、应激性血糖和糖化血红蛋白的变化。方法入选2012年1月到2013年1月在唐山市工人医院ICU及CCU住院的重症冠心病患者514例,其中男性284例,女性230例,年龄24~91岁,平均年龄(67.65±12.68)岁。根据患者年龄分为4组:A组(60岁,n=134);B组(60~69岁,n=132);C组(70~80岁,n=154);D组(≥80岁,n=94)。检测各组患者血清hs-CRP、全血血糖和全血糖化血红蛋白水平。结果与A组[(7.10±22.67)mg/L]比较,B组[(15.56±35.23)mg/L]、C组[(19.57±37.97)mg/L]、D组[(29.29±44.43)mg/L]hs-CRP呈逐渐增高趋势,差异具有统计学意义(P0.05)。与A组[(8.67±4.13)mmol/L]比较,B组[(9.26±5.93)mmol/L]、C组[(10.84±6.05)mmol/L]血糖呈逐渐增高趋势,差异具有统计学意义(P0.05)。C组与D组血糖比较无统计学差异(P0.05)。各组间糖化血红蛋白比较均无统计学差异(P0.05)。结论不同年龄重症冠心病患者入院时hs-CRP和应激性血糖随着年龄的增长而增加,而糖化血红蛋白无明显变化。
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关 键 词: | 年龄 应激 冠心病 血糖 糖化血红蛋白 高敏C反应蛋白 |
Comparison in changes of high-sensitivity C-reactive protein,stress blood glucose and glycated hemoglobin in patients with severe coronary heart disease in different ages |
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Affiliation: | LU Lin, REN Ping-xiang, YU Da-yong, LU Xin, ZHAO Jian-ling (First Department of Neurology, Tangshan Gongren Hospital, Tangshan 063000, China.) |
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Abstract: | Objective To investigate the changes of high-sensitivity C-reactive protein (hs-CRP), stress blood glucose and glycated hemoglobin in patients with severe coronary heart disease (CHD) in different ages. Methods The patients (n=514) were chosen (male 284 and female 230) aged from 24 to 91 (average age=67.65±12.68) from Jan. 2012 to Jan. 2013. All patients were divided, according to their age, into group A (age〈60, n=134), group B (aged from 60 to 69, n=132), group C (aged from 70 to 80, n=154) and group D (age≥80, n=94). The levels of serum hs-CRP, stress blood glucose and glycated hemoglobin were detected in all groups. Results The level of hs-CRP increased gradually in group B [(15.56±35.23) mg/L], group C [(19.57±37.97) mg/L] and group D [(29.29±44.43) mg/L] compared with group A [(7.10±22.67) mg/L, P〈0.05]. The level of blood glucose increased gradually in group B [(9.26±5.93) mmol/L] and group C [(10.84±6.05) mmol/L] compared with group A [(8.67±4.13) mmol/L, P〈0.05]. The comparison in blood glucose between group C and group D had no statistical difference (P〉0.05), and comparison in glycated hemoglobin among all groups had no statistical difference (P〉0.05). Conclusion The levels of hs-CRP and stress blood glucose increase as aging and level of glycated hemoglobin has no significant change in patients with severe CHD in different ages. |
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Keywords: | Age Stress Coronary heart disease Blood glucose Glycated hemoglobin High-sensitivity C-reactive protein |
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