| 超滤法除热原对川参通注射液质量的影响 |
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| 引用本文： | 龙琳,张昀. 超滤法除热原对川参通注射液质量的影响[J]. 中成药, 2001, 23(5): 328-330 |
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| 作者姓名： | 龙琳 张昀 |
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| 作者单位： | 贵州瑞和制药有限公司,贵州,贵阳,550003 |
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| 基金项目： | 科技部1999年科技型中小企业技术创新基金资助项目(00C26115200449) |
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| 摘 要： | 目的：用超滤法除热原考察对川参通注射液质量指标的影响。方法 ：选择0．6万和2万分子截留量的超滤膜对本品超滤样液，检查除热原的效果及超滤前后质量标准检测结果进行比较。结果：除热原效果理想。但超滤后多项质量指标变化较大。结论：用超滤法除中药注射剂的热原时应慎重。
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| 关 键 词： | 超滤法 川参通注射液 热原 质量指标 中药 |
| 文章编号： | 1001-1528(2001)05-0328-02 |
| 修稿时间： | 2000-08-14 |
Effect of Eliminating Pyrogens with Ultrafiltration on Quality of Chuanshentong Injection |
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| LONG Ling,ZHANG Yun. Effect of Eliminating Pyrogens with Ultrafiltration on Quality of Chuanshentong Injection[J]. Chinese Traditional Patent Medicine, 2001, 23(5): 328-330 |
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| Authors: | LONG Ling ZHANG Yun |
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| Abstract: | Objective: To study the effect of eliminating pyrogen with ultrafiltration on the quatity of Chuanshentong Injection. Methods: The sample solution was filtered with the ultrafiltration membranes of molecular weight 6000 and 20000. Then,the results of eliminating pyrogens and the examination results of quality of sample solution before and after ultrafiltration were compared.Results: The results of elminating pyrogens is satisfactory. But there are larger changes in many items of quality markers after ultrafiltration. Conclusion: Therefore, the ultrafiltration should be used with caution in eliminating pyrogens of injection of Chinese medicinals. |
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| Keywords: | ultrafiltration Chuanshentong Injection Pyrogens quality markers |
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