| 肠道菌群及其代谢产物作为阿尔茨海默病诊断生物标志物的研究进展 |
| |
| 引用本文： | 程丽珍,苗雅. 肠道菌群及其代谢产物作为阿尔茨海默病诊断生物标志物的研究进展[J]. 重庆医科大学学报, 2021, 46(11): 1352-1354 |
| |
| 作者姓名： | 程丽珍 苗雅 |
| |
| 作者单位： | 上海交通大学附属第六人民医院老年病科,上海200235 |
| |
| 基金项目： | 上海市自然科学基金资助项目（编号：19ZR1438800）。 |
| |
| 摘 要： | 阿尔茨海默病(Alzheimer's disease,AD)是老年期痴呆最常见的一种类型,随着脑-肠轴理论的提出,越来越多的研究证实AD的发生发展与肠道菌群构成及其代谢产物的改变密切相关.本文就近年肠道菌群及其代谢产物在AD领域的研究进行综述和讨论,以此为着眼点,阐述以粪便为标本的肠道菌群及其代谢产物检查作为AD诊...
|
| 关 键 词： | 阿尔茨海默病 肠道菌群 生物标志物 |
| 收稿时间： | 2021-07-05 |
Research progress of gut microbiota and its metabolites as diagnostic biomarkers of Alzheimer's disease |
| |
| Cheng Lizhen,Miao Ya. Research progress of gut microbiota and its metabolites as diagnostic biomarkers of Alzheimer's disease[J]. Journal of Chongqing Medical University, 2021, 46(11): 1352-1354 |
| |
| Authors: | Cheng Lizhen Miao Ya |
| |
| Affiliation: | Department of Geriatrics, Shanghai Jiao Tong University Affiliated Sixth People''s Hospital |
| |
| Abstract: | Alzheimer''s disease (AD) is the main cause of senile dementia. With the proposal of the brain-gut axis theory, more and more studies have confirmed the occurrence and development of AD are closely related to the change of gut microbiota and its metabolites. This article reviews and discusses the changes of fecal gut microbiota and its metabolites occurred in AD. Besides, the application prospects of fecal gut microbiota and its metabolites as AD diagnostic biomarkers are described. |
| |
| Keywords: | Alzheimer''s disease gut microbiota biomarkers |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《重庆医科大学学报》浏览原始摘要信息 |
|
点击此处可从《重庆医科大学学报》下载全文 |
