| 电生理皮质兴奋性指标在精神障碍诊疗中的价值 |
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| 引用本文： | 沈梦婷,唐莺莹,王继军.电生理皮质兴奋性指标在精神障碍诊疗中的价值[J].重庆医科大学学报,2021,46(7):794-797. |
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| 作者姓名： | 沈梦婷 唐莺莹 王继军 |
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| 作者单位： | 上海交通大学医学院附属精神卫生中心脑电影像研究室,上海200030 |
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| 基金项目： | 国家自然科学基金资助项目（编号：81871050、81971251）；上海市科委资助项目（编号：19411969100、19410710800）。 |
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| 摘 要： | 精神疾病病因机制复杂,且具有易复发、致残率高等特点,多存在脑皮质活动的兴奋性或抑制性失常.发展无创、在体、定量检测精神疾病患者大脑皮质活动的客观指标,对深入探索精神疾病的发病机制和辅助临床诊断准确性提高至关重要.基于经颅磁刺激这一新兴的无创神经调控技术,联合神经电生理检测技术的日益成熟,提供了多项大脑皮质兴奋性和抑制性...
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| 关 键 词： | 精神疾病 皮质兴奋-抑制失平衡 经颅磁刺激 |
| 收稿时间： | 2021/2/26 0:00:00 |
The value of electrophysiological cortical excitability index in the diagnosis and treatment of mental disorders |
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| Shen Mengting,Tang Yingying,Wang Jijun.The value of electrophysiological cortical excitability index in the diagnosis and treatment of mental disorders[J].Journal of Chongqing Medical University,2021,46(7):794-797. |
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| Authors: | Shen Mengting Tang Yingying Wang Jijun |
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| Institution: | Department of EEG and Neuroimaging, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine |
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| Abstract: | Mental disorders, with complex mechanisms, are characterized by high recurrence and high disability rate, while cortical excitation-inhibition imbalance is often present. It is important to develop noninvasive, in-vivo and quantified measures of cortical activity for discovering the underlying mechanism of mental disorders and improving the clinical diagnostic accuracy. Transcranial magnetic stimulation (TMS), combined with neurophysiology, has been well established to evaluate cortical excitability and inhibition. We have reviewed new progresses in the measures of cortical activity by TMS, as well as their clinical utility in evaluating cortical function and therapeutic effects of mental disorders. |
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| Keywords: | mental disorder cortical excitation-inhibition imbalance transcranial magnetic stimulation |
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