| 2型糖尿病患者高甘油三酯血症-腰围表型与颈动脉粥样硬化相关 |
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| 引用本文： | 张磊,董砚虎,徐美华,李娟娟,王晓强,王娜. 2型糖尿病患者高甘油三酯血症-腰围表型与颈动脉粥样硬化相关[J]. 中华内分泌代谢杂志, 2012, 28(1). DOI: 10.3760/cma.j.issn.1000-6699.2012.01.006 |
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| 作者姓名： | 张磊 董砚虎 徐美华 李娟娟 王晓强 王娜 |
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| 作者单位： | 266071青岛市内分泌糖尿病医院暨研究所 |
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| 摘 要： | 对2625例2型糖尿病患者的研究发现,高甘油三酯血症-腰围表型(HTWC)组患者体重指数、收缩压、HbA1C、甘油三酯、载脂蛋白(Apo)B、血尿酸、超敏C反应蛋白、肿瘤坏死因子α、颈总动脉内中膜厚度等指标均高于非HTWC组(均P＜0.05),而高密度脂蛋白胆固醇和ApoA1低于非HTWC组(P＜0.05).HTWC是2型糖尿病患者合并颈动脉粥样硬化的独立危险因素(OR 1.45,95％CI 1.07～1.96).
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| 关 键 词： | 甘油三酯 腰围 糖尿病,2型 动脉硬化 |
The hypertriglyceridaemic-waist phenotype in relation to carotid artery atherosclerosis in patients with type 2 diabetes mellitus |
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| ZHANG Lei,DONG Yan-hu,XU Mei-hua,LI Juan-juan,WANG Xiao-qiang,WANG Na. The hypertriglyceridaemic-waist phenotype in relation to carotid artery atherosclerosis in patients with type 2 diabetes mellitus[J]. Chinese Journal of Endocrinology and Metabolism, 2012, 28(1). DOI: 10.3760/cma.j.issn.1000-6699.2012.01.006 |
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| Authors: | ZHANG Lei DONG Yan-hu XU Mei-hua LI Juan-juan WANG Xiao-qiang WANG Na |
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| Abstract: | Among 2625 patients with type 2 diabetes,body mass index,systolic blood pressure,HbA1C,triglyceride,ApoB,serum uric acid,highly-sensitive C reactive protein,tumor necrosis factor α levels,and common carotid artery intima-media thickness in hypertriglyceridemic-waist ( HTWC ) phenotype group were higher than those in non-HTWC group,while high-density lipoprotein cholesterol and ApoA1 levels were lower( all P＜0.05 ).HTWC phenotype was an independent risk factor for atherosclerosis of carotid artery in patients with type 2 diabetes mellitus (OR 1.45,95％CI 1.07-1.96). |
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| Keywords: | Triglycerides Waist circumference Diabetes mellitus,type2 Atherosclerosis |
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