| 代谢组学技术在糖尿病研究中的应用 |
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| 引用本文： | 李海静,吴胜明,程建华,董方霆.代谢组学技术在糖尿病研究中的应用[J].中华内分泌代谢杂志,2012,28(1). |
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| 作者姓名： | 李海静 吴胜明 程建华 董方霆 |
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| 作者单位： | 国家生物医学分析中心,北京,100850 |
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| 基金项目： | 国家自然科学基金，重大传染病专项 |
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| 摘 要： | 糖尿病是典型的代谢性疾病,其危害主要来自高发的并发症,并最终导致高致死率和致残率.目前糖尿病确切机制仍然未知,也未见有效的根治方法,故预防成为重中之重.代谢组学作为一种能够识别和测量生物体整体代谢变化的新技术,已被广泛应用到糖尿病的相关研究中,并显现出在疾病防治中的巨大潜力.
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| 关 键 词： | 代谢组学 糖尿病 代谢性疾病 生物标志物 |
Metabonomics in diabetes research |
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| LI Hai-jing,WU Sheng-ming,CHENG Jian-hua,DONG Fang-ting.Metabonomics in diabetes research[J].Chinese Journal of Endocrinology and Metabolism,2012,28(1). |
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| Authors: | LI Hai-jing WU Sheng-ming CHENG Jian-hua DONG Fang-ting |
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| Abstract: | Diabetes mellitus is a typical metabolic disease.Its complications cause the main damage and lead to high mortality and disability eventually.The exact mechanism of diabetes is still unknown at present,and no radical cure of it is available.Therefore,the prevention of diabetes has become a priority.Metabolomics as a new technology can identify and measure the entire metabolic changes in the organism,and therefore has been widely applied to diabetes related studies with its enormous potential. |
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| Keywords: | Metabonomics Diabetes mellitus Metabolic disease Biomarker |
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