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丙硫咪唑等药物驱治肠道线虫病的疗效观察
引用本文:吴中兴 刘浩坤 等. 丙硫咪唑等药物驱治肠道线虫病的疗效观察[J]. 徐州医学院学报, 1990, 10(1): 33-36
作者姓名:吴中兴 刘浩坤 等
作者单位:[1]徐州医学院 [2]江苏赣榆县防疫站
摘    要:丙硫咪唑400mg、400mg×2顿服,治疗钩虫140例,虫卵阴转率为86.8%-97%,蛔虫卵阴转率为95.6%-96.9%,鞭虫卵阴为43.2%-52.7%。200mg和400mg治疗幼儿晓虫,虫卵阴转率为96.5%-98.9%。比利时的甲苯咪唑口服液200mgbid×3d,钩虫卵阴转率为94.4%,两药副反应轻微、暂短,均可自行消失。

关 键 词:丙硫咪唑 甲苯咪唑口服液 钩虫感染 蛲虫感染 寄生虫学 治疗

THE EFFICACY OF ALBENDAZOLE AND ORAL MEBENDAZOLE SUSPENSION IN THE TREATMENT OF INTESTINAL NEMATODE INFECTIONS
Wu Zhongxing. THE EFFICACY OF ALBENDAZOLE AND ORAL MEBENDAZOLE SUSPENSION IN THE TREATMENT OF INTESTINAL NEMATODE INFECTIONS[J]. Acta Academiae Medicinae Xuzhou, 1990, 10(1): 33-36
Authors:Wu Zhongxing
Abstract:A total of 364 cases of intestinal nematode infections, 140 with hookworm and 224 with pinworm, were selected for study. The hookworm g-roup received albendazole 400 mg stat., 400 mg q.d for 2 days or 400 mg b.i.d. for one day. The egg negative conversion rates achieved ( Kato-Katz technique ) were 86.8%,92.8% and 97.0% respectively. The egg negative conversion rates were 95.6-96.9%for ascaris and were 43.2-52.7%for tric-huris. Oral mebendazole suspension 200mg b. i. d. for three days was tried to treat 18 cases of hookworm infection and the egg negative conversion rate was 94.4%, while that of the control group of 19 cases treated with levamisole 2mg/kg q.d for three days was 68.4%. The pinworm group was treated with stat. dose of albendazole 200 or 400mg and the egg negative conversion rates (cellophane technique) were 96.5%and 98.9% respectively. The side reactions of albendazole and mebendazole were mild, transient and self-limited.
Keywords:albendazole  mebendazole   oral suspension  hookworm infection  pinworm infection  egg negative conversion rates  parasitology
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