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Dietary selenium intake and risk of type 2 diabetes in a female population of western Algeria
Affiliation:1. Faculty of Science and Technology of Settat, Laboratory of Health Sciences and Technologies, Higher Institute of Health Sciences of Settat, Settat, Morocco;2. Laboratory of Health Sciences and Technologies, Higher Institute of Health Sciences of Settat, Settat, Morocco;3. Paediatrician Service B and Dietary unit, University Hospital Centre Mohamed VI of Marrakesh, Marrakesh, Morocco;1. Service de médecine et de spécialités médicales, centre hospitalier universitaire de Tengandogo, Ouagadougou, Burkina Faso;2. Service d’information et d’épidémiologie, centre hospitalier universitaire de Tengandogo, Ouagadougou, Burkina Faso;3. Service de néphrologie, centre hospitalier universitaire de Yalgado-Ouedraogo, Ouagadougou, Burkina Faso;1. Service d’hépato-gastroentérologie, Cliniques universitaires Saint-Luc, UCLouvain, 10, avenue Hippocrate, 1200 Bruxelles, Belgique;2. Laboratory of Hepatology and Gastroenterology, Institut de recherche expérimentale et clinique (IREC), Université catholique de Louvain, UCLouvain, 52, avenue Mounier, 1200 Bruxelles, Belgique;1. FSESNV, département des êtres vivants, université Larbi Tébessi, Tébessa 12000, Algérie;2. FSESNV, département de biologie appliquée, université Larbi Tébessi, Tébessa, 12000, Algérie;3. Laboratoire eau et environnement, université Larbi Tébessi, Tébessa, 12000, Algérie;4. Laboratoire de nutrition et technologie alimentaire (LNTA), université de Constantine 1, Constantine, Algérie
Abstract:Several studies have raised possible associations between high selenium exposure and type 2 diabetes. Here we investigate the association between dietary selenium intake and the risk of type 2 diabetes in a female population from western Algeria. The analytical study included a total sample of 290 women, 140 type 2 diabetics and 150 controls. The dietary selenium intake has been measured by a 72-hour dietary recall. The odds ratio (OR) and the corresponding 95% confidence interval (CI) were used to determine the relationship between dietary selenium intake and diabetes through logistic regression. The quartile in the range of recommended dietary selenium intake was considered as a reference. The average level of dietary selenium intake was 72.40 μg/day in diabetics and 70.30 μg/day in controls (P > 0.05). The odds ratio for diabetes, comparing the highest quartile of dietary selenium intake to the reference quartile was 2.21 (95% CI 1.06–4.38; P = 0.036). While the lowest quartile had an odds ratio of 2.52 (95% CI 1.25–5.09; P = 0.010). In conclusion, this study indicates that there is a significant association between the risk of type 2 diabetes and both high and low dietary selenium intake.
Keywords:Selenium  Type 2 diabetes  Dietary intake  Sélénium  Diabète de type 2  Apport alimentaire
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