首页 | 本学科首页   官方微博 | 高级检索  
     


Off-Pump Myocardial Revascularization in a High-Risk Patient with Essential Thrombocythemia
Authors:Ahmad K. Darwazah  Hamad Madi  Rami Zagha  Yahia Hawash
Abstract:Essential thrombocythemia is a rare type of myeloproliferative disorder. Cerebral, myocardial, and peripheral thrombosis are all frequent complications of the disease.A 71-year-old man presented with severe coronary artery disease, associated with cerebral vascular ischemic changes and erythromelalgia. His platelet count was 1,486 ×103/μL. The patient underwent successful myocardial revascularization by means of an off-pump technique after his platelet count had been reduced by hydroxycarbamide administration.We conclude that the use of off-pump cardiopulmonary bypass in high-risk patients with essential thrombocythemia is safe. Reducing platelet count via the administration of hydroxycarbamide and the careful balancing of antiplatelets and anticoagulants is crucial in determining the outcome of surgery.
Keywords:Blood platelets/metabolism   coronary artery bypass   off-pump   graft survival   hydroxycarbamide   Janus kinase 2   mega-karyocytes   platelet count   plateletpheresis   thrombocythemia   essential/blood/drug therapy   treatment outcome   vascular patency
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号