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不同产地冬虫夏草清除羟自由基作用的研究
引用本文:蔡仲军,陈仕江,尹定华,张艳.不同产地冬虫夏草清除羟自由基作用的研究[J].中草药,2004,35(1):57-59.
作者姓名:蔡仲军  陈仕江  尹定华  张艳
作者单位:重庆市中药研究院,重庆,400065
基金项目:国家自然科学基金项目 (3 0 2 40 0 67)
摘    要:目的 比较不同产地冬虫夏草对羟自由基的清除作用。方法 采用邻二氮菲-Fe^2 氧化法检测不同产地冬虫夏草水提液对H2O2/Fe^2 体系产生的羟自由基的清除作用。结果 来自西藏那吐地区、云南滇西北地区和四川川西北地区的冬虫夏草均对Fenton反应产生的羟自由基有显著或极显著的清除作用,且来自不同微生态环境的样品之间的清除作用差异比来自不同主产区样品之间的清除作用差异更明显。结论 冬虫夏草水提液有明显地清除羟自由基的作用,且微生态环境对该作用有较大的影响。

关 键 词:冬虫夏草  羟自由基  微生态环境  相互变异室
文章编号:0253-2670(2004)01-0057-03
收稿时间:2003/5/27 0:00:00

Scavenging effect of Cordyceps growing in different environment on hydroxyl radical
CAI Zhong-jun,CHEN Shi-jiang,YIN Ding-hua and ZHANG Yan.Scavenging effect of Cordyceps growing in different environment on hydroxyl radical[J].Chinese Traditional and Herbal Drugs,2004,35(1):57-59.
Authors:CAI Zhong-jun  CHEN Shi-jiang  YIN Ding-hua and ZHANG Yan
Institution:Chongqing Institute of Chinese Materia Medica,Chongqing 400065,China;Chongqing Institute of Chinese Materia Medica,Chongqing 400065,China;Chongqing Institute of Chinese Materia Medica,Chongqing 400065,China;Chongqing Institute of Chinese Materia Medica,Chongqing 400065,China
Abstract:Object To investigate and compare the scavenging effect of Cordyceps growing in different environment on hydroxyl radical. Methods 10-Phennanthroline-Fe 2 oxidative assay was used to observe the effect of scavenging hydroxyl radical from H_2O_2/Fe 2 system by the aquenous extracts of Cordyceps. Results Cordyceps from Naqu of Xizang,northwest Yunnan,and northwest Sichuan all showed us the significant effect on scavenging of hydroxyl radical produced from Fenton Reaction. The biggest values of MDR among Cordyceps specimens from various microecological environment surpassed that among specimens of Naqu of Xizang,northwest Yunnan,and northwest of Sichuan. Conclusion The aquenous extracts of Cordyceps could scavenge the hydroxyl radical from Fenton Reaction. The microecological environment for Cordyceps growing has an significant effect on its scavenging action.
Keywords:Cordyceps  hydroxyl radical  microecological effect  mutual different rate (MDR)  
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