| 沙棘籽油对缺血性脑梗塞大鼠血液流变学的影响 |
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| 引用本文： | 程体娟,高丽萍,王玉斌,张坚,孙以方,李冬瑜.沙棘籽油对缺血性脑梗塞大鼠血液流变学的影响[J].中药药理与临床,2002,18(2):14-15. |
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| 作者姓名： | 程体娟 高丽萍 王玉斌 张坚 孙以方 李冬瑜 |
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| 作者单位： | 1. 兰州医学院
2. 甘肃省人民医院影像诊断中心,兰州,730000 |
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| 基金项目： | 甘肃省自然科学基金项目(ZR-97-101) |
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| 摘 要： | 本文旨在探讨沙棘籽油对缺血性脑梗塞大鼠血液流变学的影响。采用大脑中动脉阻断术 (MCAO)制作动物模型 ,用旋转式血液粘度计测定大鼠全血粘度、血浆粘度、全血还原粘度、红细胞压积、红细胞聚集指数和红细胞变形指数。结果表明沙棘籽油能显著降低全血粘度、血浆粘度和全血还原粘度 ,并能降低红细胞聚集指数。提示沙棘籽油能显著改善脑梗塞大鼠的血液流变学性质。
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| 关 键 词： | 沙棘籽油 尼莫地平 络欣通 血液流变学 |
The effect of seed oil of Hippophae rhamnoides L. (SOHR) on hemorrheology of cerebrel infarction in rats |
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| Cheng Tijuan,Gao Liping,Zhang Jan,wang Yubin ,Sun Yifang,Li Dongyu.The effect of seed oil of Hippophae rhamnoides L. (SOHR) on hemorrheology of cerebrel infarction in rats[J].Pharmacology and Clinics of Chinese Materia Medica,2002,18(2):14-15. |
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| Authors: | Cheng Tijuan Gao Liping Zhang Jan wang Yubin Sun Yifang Li Dongyu |
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| Institution: | Cheng Tijuan,Gao Liping,Zhang Jan,wang Yubin 1,Sun Yifang,Li Dongyu |
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| Abstract: | To study the effect of SOHR on hemorrheology of cerebral infarction rats, the ischemic cerebral infarction model was made by middle cerebral artery occlusion (MCAO). Blood viscosity, plasma viscosity, blood reduced viscosity, hematocrit, red blood cell aggregation index, red blood cell deformation index were determined. The results showed that SOHR could reduce significantly blood viscosity, plasma viscosity and blood reduced viscosity, it also could reduce red blood cell aggregation index. |
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| Keywords: | seed oil of Hippophae rhamnoides L nimodipine loxintong hemorrheology viscosity |
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