吲哚青绿血管造影观察青光眼患者的盘周脉络膜血液供应分水带

目的 观察青光眼患者吲哚青绿血管造影（ICGA）中盘周脉络膜血液供应分水带与视盘的相对位置关系，探讨青光眼视神经病变的发病机制。 方法 对青光眼患者31例31只眼和对照组37例37只眼进行ICGA和荧光素眼底血管造影(FFA)同步检查。青光眼患 者中原发性开角型青光眼（POAG）17例17只眼、正常眼压性青光眼（NTG）14例14只眼。对比分析30 s内的ICGA和FFA图像，根据分水带与视盘的相对位置关系 ，将分水带分为3型。I型：分水带不包围视盘或未被观察到；II型：分水带部分包围视盘；III型：分水带完全包围视盘。并根据分水带类型记分（I型=1；II型=2,III型=3）。 结果 87.1%的青光眼患者的分水带全部或部分包围视盘，而在对照组中仅为56.8%的分水带全部或部分包围视盘，二者比较差异有非常显著性的意义（χ2=7.369；P=0.007）。青光眼组的分值显著大于对照组（t=3.001，P=0.004）。 结论 青光眼患者的盘周脉络膜分水带的位置较正常眼更多地包围视盘，提示青光眼视神经病变的发病机制可能与盘周脉络膜血液供应状态有关。 （中华眼底病杂志，2004，20：218-220）

Observation of the peripapillary watershed zones in glaucoma by indocyanine green angiography

Objective To observe the location of the watershed zones of the choroidal blood supply relative to the optic disc in glaucoma by indocyan ine green angiography, and to investigate the mechanisms in the development of glaucomatous neuropathy. Method Simultaneous ICGA and FFA were performed on 31 eyes of 31 patients with glaucoma (17 of POAG, 14 of NTG) and 37 eyes of 37 control subjects. The watershed zones were classified into three types according to their location relative to the optic disc: by type I, no water shedzone around the optic disc; type II, the optic disc surrounded partially by watershed zone; type III, the optic disc surrounded completely by watershed zone. Each of the watershed zone types was scored (i.e., type I=1, type II=2, type III=3). Results In 87.1% of the glaucomatous eyes , the watershed zones included or partially included the optic disc. However, the figure in the control group was 56.8%. The glaucoma group had a higher score of watershed zone type than the control group. Conclusions The mechanisms in the development of glaucomatous neuropathy are correlative to the choroidal blood supply around the optic disc. (Chin J Ocul Fundus Dis，2004，20：218-220)