中、长链脂肪乳剂对肝硬变门脉高压手术前后脂肪廓清的影响

选择肝硬变门脉高压病人１５例，随机分为两组：长链肪乳剂组，中／长链脂肪乳剂组。ＬＣＴ旨肪有源由２０％－Ｉｎｔｒａｌｉｐｉｄ提供，ＭＣＴ组由２０％－ＬｉｐｏｆｕｎｄｉｎＭＣＴ／ＬＣＴ组成，糖脂供热比为２：１，全部营养素配制成全营养混合液（ＴＮＡ），连续观察１周，在术前、术后１天、７天作脂肪廓清试验（ＶＦＴＴ）。经高效液相色谱ＨＰＬＣ）测定注射后５、３０、６０及９０分钟时亚油酸、亚麻酸、辛酸及癸酸的含

Influence of the fat emulsion containing MCT on IVFTT in patients with livercirrhosis and portal hypertension

Fifteen patients with liver cirrhosis and portal hypertension were randomly assigned totwo PN groups: LCT group (n= 8) and MCT/LCT group. The lipid energy of LCT group was suppliedby 20% Intralipid and MCT/LCT-group was supplied by 20%-Lipofundin. The energy rate of the glucose and fat emulsion is 2: 1. The PN solution was infused by TNA per day for 7 days. At the pre-OP.POD, and POD: IVFTT were tested in two groups, and the octanoic. deconic. linoleic. Iinolenic weremeasured by HPLC after the infusion at 5. 30. 60. 90min. The IVFTT showed that fat emulsion elimination at POD, was faster than pre-OP in LCT-group, but in MCT/LCT group the elimination rate maintained higher level as compared with LCT-group (P<0. of). The metabolic clearance of fat emulsioncontaining MCT was more rapidy than LCT at preparation and postoperation.