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Reversibility of anatomical and functional asplenia by chronic transfusion in a child with sickle cell anemia
Authors:M F Ozkaynak  J A Ortega
Affiliation:Division of Hematology/Oncology, Childrens Hospital, Los Angeles, California 90027.
Abstract:We describe a 13-year-old black girl with sickle cell disease in whom spleen regrew after autosplenectomy during the course of a transfusion program for a cerebrovascular accident. This case illustrates the remarkable regrowth potential of the shrunken and fibrotic spleen when sickled red cells are replaced with normal cells.
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