| 神经生长因子基因在大鼠心肌组织中的表达 |
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| 引用本文： | 丁斐,顾晓松,陈峰.神经生长因子基因在大鼠心肌组织中的表达[J].南通医学院学报,2001,21(3):224-225,228. |
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| 作者姓名： | 丁斐 顾晓松 陈峰 |
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| 作者单位： | 南通医学院卫生系 |
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| 基金项目： | 国家自然科学基金资助项目 ( No.30 0 70 2 55)，江苏省教育厅科研项目 ( OOKJD30 10 0 0 7) |
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| 摘 要： | 目的：观察神经生长因子（NGF）基因在生后不同时期大鼠心肌组织中的表达，方法：采用RT－PCR方法，半定量分析生后1天、15天、30天、60天、120天，360天大鼠心肌组织中NGFmRNA含量。结果：大鼠生后1天，心肌组织即NGFmRNA的表达；随着生后发育过程，表达量逐步增加，30天时达峰值；此后随鼠龄的增加，表达量呈级慢下降趋势，结论：大鼠心肌组织中NGFmRNA的表达量，随鼠龄的增加，而呈现出先升后降的动态变化趋势。
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| 关 键 词： | 神经生长因子 mRNA 大鼠 心肌组织 基因表达 |
| 文章编号： | 1000-2057(2001)03-0224-02 |
THE NGF GENE EXPRESSION IN RAT MYOCARDIUM |
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| Ding Fei,Gu Xiaosong,Chen Feng.THE NGF GENE EXPRESSION IN RAT MYOCARDIUM[J].ACTA Academiae Medicinae Nantong,2001,21(3):224-225,228. |
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| Authors: | Ding Fei Gu Xiaosong Chen Feng |
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| Institution: | Ding Fei,1Gu Xiaosong,Chen Feng |
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| Abstract: | Objective:To study NGF gene expression in the myocardium of rat during postnatal various period. Methods: NGF mRNA expression levels in the myocardium of rat 1d, 15d, 30d, 60d, 120d, 360d after born were investigated by the RT-PCR method, as a hamiquantity assay. Results: NGF mRNA in rat myocardium appeared in newborn. During the developmental period, NGF mRNA expression was gradually increased, and it reached the peak at 30th day after born. Then it slowly decreased following the extension of age. Conclusion :The expression levels of NGF mRNA in rat myocardium was possessed of the changeable character during postnatal various period, that was increased first and decreased then. |
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| Keywords: | Myocardium NGF mRNA Rat |
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