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粒生素促进恶性肿瘤病人化疗引起的白细胞减少症的恢复
引用本文:李志玖,莫正英,熊奎. 粒生素促进恶性肿瘤病人化疗引起的白细胞减少症的恢复[J]. 中国实验血液学杂志, 2002, 10(1): 85-86
作者姓名:李志玖  莫正英  熊奎
作者单位:湖北省郧阳医学院附属太和医院肿瘤科,十堰,442000
摘    要:~~粒生素促进恶性肿瘤病人化疗引起的白细胞减少症的恢复@李志玖$湖北省郧阳医学院附属太和医院肿瘤科!十堰442000@莫正英$湖北省郧阳医学院附属太和医院肿瘤科!十堰442000@熊奎$湖北省郧阳医学院附属太和医院肿瘤科!十堰442000~~~~~~

关 键 词:粒生素 粒细胞集落刺激因子 恶性肿瘤 白细胞减少症 化疗
修稿时间:2001-07-06

Lishengsu Promotes the Recovery of Chemotherapy-Induced Leukopenia in Patients with Malignant Tumors
Zhi-Jiu Li,Zheng-Ying Mo,Kui Xiong. Lishengsu Promotes the Recovery of Chemotherapy-Induced Leukopenia in Patients with Malignant Tumors[J]. Journal of experimental hematology, 2002, 10(1): 85-86
Authors:Zhi-Jiu Li  Zheng-Ying Mo  Kui Xiong
Affiliation:Department of Oncology, The Affiliated Taihe Hospital, Yunyang Medical College of Hubei Province, Shiyan 442000, China.
Abstract:In order to investigate the therapeutic effects of Lishengsu, a domestic preparation of recombinant human granulocyte colony stimulating factor, the recovery of leukopenia was observed in 58 patients with malignant tumors after chemotherapy. In these patients, 7 cases were in first cycle of chemotherapy and 51 were given in repeated cycles. When blood leukocyte level decreased to less than 3x10(9)/L, Lishengsu was subcutaneously injected for 3-5 days at a dose of 75 microgram or 150 microgram per day. The results showed that Lishengsu remarkably alleviated the degree of leukopenis and accelerated the leukocyte counts recovered to normal level. The promotive effects of Lishengsu to recovery of leukopenia were dependent on degree of leukopenia at start of administration of Lishengsu. The curative effect of Lishengsu to chemotherapy-induced leukopenia was reliable with slight side-effects
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