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妊娠期空气颗粒物暴露与早产
引用本文:陶瑞文, 夏珣, 黄锟, 童世庐, 陶芳标. 妊娠期空气颗粒物暴露与早产[J]. 中国公共卫生, 2016, 32(2): 239-243. DOI: 10.11847/zgggws2016-32-02-30
作者姓名:陶瑞文  夏珣  黄锟  童世庐  陶芳标
作者单位:1.安徽医科大学公共卫生学院儿少卫生与妇幼保健学系, 安徽合肥 230032;;2.安徽人口健康与优生省级实验室;;3.澳大利亚昆士兰理工大学公共卫生和生物医学创新研究所
基金项目:国家自然科学基金(81330068;81373012)
摘    要:越来越多的研究证据表明,孕妇妊娠期颗粒物暴露可通过母体影响胎儿的发育,导致早产、低出生体重、胎儿生长受限和潜在的不良心血管和呼吸道结局。但研究结果并不一致,且生物学机制尚不明确。本文通过对近年来国内外主要几种颗粒物人体暴露来源和其对早产影响及生物学机制作一简要综述,为控制空气污染和减少早产等不良妊娠结局的发生以及进一步探讨其可能的生物学机制提供基础依据。

关 键 词:颗粒物  总悬浮颗粒物(TSP)  可吸入颗粒物(PM10)  细颗粒物(PM2.5)  早产
收稿时间:2015-05-25

Maternal exposure to particulate matter and preterm delivery
TAO Rui-wen, XIA Xun, HUANG Kun.et al, . Maternal exposure to particulate matter and preterm delivery[J]. Chinese Journal of Public Health, 2016, 32(2): 239-243. DOI: 10.11847/zgggws2016-32-02-30
Authors:TAO Rui-wen  XIA Xun  HUANG Kun.et al
Affiliation:1.Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, Anhui Province 230032, China
Abstract:More and more research evidences indicate that the exposure to particulate matter during pregnancy can impact the development of the fetus,resulting in preterm birth,low birth weight,growth restriction,and potentially adverse cardiovascular and respiratory outcomes.However,the results were inconsistent and the biological mechanism was not clear.This review summarizes on harmful effects of several main particulate matter exposures on preterm birth and the sources of the exposures and provides references for controlling air pollution,reducing the occurrence of adverse pregnancy outcomes such as preterm delivery,and exploring possible biological mechanism of the effects.
Keywords:particulate matter  total suspended particulate  PM10  PM2.5  preterm delivery
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