奥扎格雷治疗短暂性脑缺血发作的疗效

目的:研究奥扎格雷治疗短暂性脑缺血发作(TIA)的临床效果。方法:将符合标准的入选病例分为:治疗组41例,给予奥扎格雷160 mg·d~(-1),分2次静脉滴注;对照组40例,给予阿司匹林150 mg·d~(-1),口服,2组疗程均为14 d,并于治疗结束后随访60 d。结果:2组临床疗效比较,差异有显著意义(P＜0．05);治疗组较对照组的基本治愈率明显提高(75%vs 50%,P＜0．05)。结论:奥扎格雷治疗TIA效果确切,可降低TIA病人脑梗死的发生率。

Therapeutic effect of ozagrel in treating transient cerebral ischemic attack

AIM:To study the clinical effect of treating transient cerebral ischemic (TIA) with ozagrel. METHODS:Patients coincided with the selecting standard were divided into a trial group,41 patients, treating with ozagrel twice a day,totaling 160mg·d~(-1),iv,gtt;and control group,40 patients,giving oral aspirin once a day,totaling 150mg·d~(-1).The course of treatment for both groups was 14d for each;with follow- up survey of 60d.RESULTS:There was significant difference between the clinical effects of the two groups (P＜0.05),with the basic cure rate of trial group obviously higher than that of the controlled group (75% vs 50%,respectively,P＜0.05).CONCLUSION:Treatment of TIA with ozagrel is definitely effective and may reduce the incidence of cerebral infarction.